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The British Journal of Psychiatry 162: 835-837 (1993)
© 1993 The Royal College of Psychiatrists

Worsening of pica as a symptom of depressive illness in a person with severe mental handicap

SH Jawed, VH Krishnan, VP Prasher and JA Corbett
Weston Hospital, Leamington Spa, Warwickshire.

The case of a person with severe mental handicap whose pica became uncontrollable during episodes of depressive illness is described. Treatment of the depression with lofepramine markedly reduced the pica, and withdrawal of lofepramine led to recurrence. It is suggested that biological symptoms of depression should be monitored in people with severe mental handicap who show significant episodic worsening of long- standing repetitive behaviour.


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