BJP College Seminars Series
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Psychiatric Bulletin Advances in Psychiatric Treatment All RCPsych Journals
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Submit an eLetter
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Johnston, A. M.
Right arrow Articles by Eagles, J. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Johnston, A. M.
Right arrow Articles by Eagles, J. M.

The British Journal of Psychiatry 175: 336-339 (1999)
© 1999 The Royal College of Psychiatrists

Lithium-associated clinical hypothyroidism. Prevalence and risk factors

AM Johnston and JM Eagles
Psychiatric Unit, Hairmyres Hospital, East Kilbride, Lanarkshire.

BACKGROUND: Rates of, and risk factors for, lithium-associated clinical hypothyroidism are uncertain. AIMS: To determine prevalence of and risk factors for clinical hypothyroidism in patients treated with lithium carbonate. METHOD: Retrospective case-note review of 718 patients who had undergone serum lithium estimation during a 15-month period. Patients on thyroxine had a more detailed review. RESULTS: The prevalence of clinical hypothyroidism during lithium treatment was 10.4%. The main risk factor was female gender (women 14% v. men 4.5%). Women were at highest risk during the first two years of lithium treatment, and women starting lithium aged 40-59 years had the greatest prevalence (> 20%). No equivalent risk factors emerged in men, although, like women, their prevalence of hypothyroidism was substantially higher than community rates. CONCLUSIONS: The high rates of clinical hypothyroidism identified may call for a review of the drug information given to women, particularly to those starting lithium in middle age. Consideration should be given to screening for thyroid antibodies before treatment in high-risk cases. Monitoring of thyroid function should take into account gender, age and stage of lithium treatment.


This article has been cited by other articles:


Home page
 J PsychopharmacolHome page
C. Livingstone and H. Rampes
Lithium: a review of its metabolic adverse effects
J Psychopharmacol, May 1, 2006; 20(3): 347 - 355.
[Abstract] [PDF]

Home page
 Am. J. PsychiatryHome page
M. E. Fisfalen, T. G. Schulze, J. R. DePaulo Jr., L. J. DeGroot, J. A. Badner, and F. J. McMahon
Familial Variation in Episode Frequency in Bipolar Affective Disorder
Am J Psychiatry, July 1, 2005; 162(7): 1266 - 1272.
[Abstract] [Full Text] [PDF]

Home page
 AJGPHome page
K. I. Shulman, K. Sykora, S. S. Gill, M. Mamdani, G. Anderson, C. Marras, W. P. Wodchis, P. E. Lee, and P. Rochon
New Thyroxine Treatment in Older Adults Beginning Lithium Therapy: Implications for Clinical Practice
Am J Geriatr Psychiatry, April 1, 2005; 13(4): 299 - 304.
[Abstract] [Full Text] [PDF]

Home page
 FocusHome page
R. M.A. Hirschfeld, C. L. Bowden, M. J. Gitlin, P. E. Keck, R. H. Perlis, T. Suppes, M. E. Thase, and K. D. Wagner
Practice Guideline for the Treatment of Patients With Bipolar Disorder (Revision)
Focus, January 1, 2003; 1(1): 64 - 110.
[Full Text] [PDF]

Home page
 Psychiatr. Bull.Home page
J. M. EAGLES
Monitoring patients on lithium
Psychiatr. Bull., December 1, 2002; 26(12): 468 - 469.
[Full Text]

Home page
 Br. J. PsychiatryHome page
U. Leutgeb
Ambient iodine and lithium-associated clinical hypothyroidism
The British Journal of Psychiatry, May 1, 2000; 176 (5): 495a - 496a.
[Full Text] [PDF]

Home page
 Br. J. PsychiatryHome page
S. Bhandari
Lithium-induced hypothyroidism
The British Journal of Psychiatry, January 1, 2000; 176 (1): 95 - 95.
[Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Psychiatric Bulletin Advances in Psychiatric Treatment All RCPsych Journals
Copyright © 1999 The Royal College of Psychiatrists.