This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Submit an eLetter
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by BROWNE, R.
Right arrow Articles by WALSH, D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by BROWNE, R.
Right arrow Articles by WALSH, D.
The British Journal of Psychiatry (2000) 176: 369-371
© 2000 The Royal College of Psychiatrists

Labour and delivery complications at birth and later mania

An Irish case register study

ROY BROWNE, MRCPsych, MAJELLA BYRNE, MSc, MARY MORRIS, BSc and EADBHARD O'CALLAGHAN, MD

Cluain Mhuire Community Psychiatric Service

NIAMH MULRYAN, MRCPsych and ANN SCULLY, MRCPsych

St Loman's Hospital

ANTHONY KINSELLA, MSc

Dublin Institute of Technology, Dublin, Ireland

THOMAS F. McNEIL, PhD

Department of Community Medicine, Lund University, Sweden

DERMOT WALSH, FRCPsych

St Loman's Hospital and Mental Health Section, Health Research Board, Ireland

Declaration of interest This study was funded by the Health Research Board, Ireland, and the Stanley Foundation.

Correspondence: Dr E. O'Callaghan, Cluain Mhuire Community Psychiatric Service, Newtownpark Avenue, Blackrock, County Dublin, Ireland. Tel: 353-1-2833766; fax: 353-1-2833886

Background Several reports postulate that manic depression and schizophrenia share environmental risk factors. Although obstetric adversity has been suggested as a risk factor for schizophrenia, few studies have examined its relationship to bipolar affective disorder.

Aims To assess the rate of obstetric complications incurred by patients with mania compared with controls.

Method From the Dublin Psychiatric Case Register we identified individuals with a discharge diagnosis of mania and traced their birth records. Each case was matched with a control of the same gender, born in the same hospital, in the same year, matched for maternal age, parity and social class. Two obstetric complication scales were used to make blind evaluations of labour and delivery data.

Results Patients with mania did not experience a greater frequency or severity of labour and delivery complications than their matched controls. Rates of obstetric adversity were unrelated to the presence or absence of family history of psychiatric disorder. Obstetric adversity was unrelated to the age at first diagnosis.

Conclusions These findings suggest that obstetric adversity is not a risk factor for later mania.




This article has been cited by other articles:


Home page
 J PsychopharmacolHome page
G. Goodwin and Consensus Group of the British Association for Psy
Evidence-based guidelines for treating bipolar disorder: revised second edition--recommendations from the British Association for Psychopharmacology
J Psychopharmacol, June 1, 2009; 23(4): 346 - 388.
[Abstract] [PDF]

Home page
 Br. J. PsychiatryHome page
J. Scott, Y. McNeill, J. Cavanagh, M. Cannon, and R. Murray
Exposure to obstetric complications and subsequent development of bipolar disorder: Systematic review
The British Journal of Psychiatry, July 1, 2006; 189(1): 3 - 11.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. PsychiatryHome page
T. Kieseppa, T. Partonen, J. Haukka, J. Kaprio, and J. Lonnqvist
High Concordance of Bipolar I Disorder in a Nationwide Sample of Twins
Am J Psychiatry, October 1, 2004; 161(10): 1814 - 1821.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. PsychiatryHome page
B. D. Kelly, L. Feeney, E. O'Callaghan, R. Browne, M. Byrne, N. Mulryan, A. Scully, M. Morris, A. Kinsella, N. Takei, et al.
Obstetric Adversity and Age at First Presentation With Schizophrenia: Evidence of a Dose-Response Relationship
Am J Psychiatry, May 1, 2004; 161(5): 920 - 922.
[Abstract] [Full Text] [PDF]

Home page
 J PsychopharmacolHome page
G. M. Goodwin
Evidence-Based Guidelines for Treating Bipolar Disorder: Recommendations from the British Association for Psychopharmacology
J Psychopharmacol, June 1, 2003; 17(2): 149 - 173.
[Abstract] [PDF]