HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS Psychiatric Bulletin Advances in Psychiatric Treatment All RCPsych Journals		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Submit an eLetter Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by PATERNITI, S. Articles by ALPÉROVITCH, A. Search for Related Content PubMed PubMed Citation Articles by PATERNITI, S. Articles by ALPÉROVITCH, A.

Low blood pressure and risk of depression in the elderly

A prospective community-based study

Institut National de la Santé et de le Recherche Medicale, Hôpital Fernand Widal, Paris, France

Declaration of interest The project was partly funded by a grant from the Merck, Sharp and Dohme-Chibret Company and EISAI (France).

Correspondence: Dr Sabrina Paterniti, INSERM U360, Hôpital La Salpêtrière, 75651 Paris Cedex 13, France. Tel: 0083 1 42162554; Fax: 0033 1 42162541

Background The relationship between depression and low blood pressure is unclear.

Aims To examine the temporal relation between low blood pressure and depression in a two-year follow-up.

Method The study group consisted of 1389 subjects aged 59-71 years; 1272 (92%) were examined after two years. Subjects completed the Center for Epidemiological Studies—Depression (CES—D) and the Spielberger inventory scales to assess depressive and anxiety symptoms respectively. Data were collected on socio-demographic characteristics, smoking and drinking habits, medical history, drug use and blood pressure measures.

Results Among 1112 subjects who were considered as non-depressed at baseline, logistic regression models showed that low diastolic blood pressure (DBP) and decrease of blood pressure were predictors of high depressive symptomatology at follow-up. Baseline high CES—D scores did not predict low blood pressure two years after.

Conclusions In our study, low blood pressure was a risk factor for, but not a consequence of, high depressive symptomatology.

This article has been cited by other articles:

				B. Hildrum, A. Mykletun, J. Holmen, and A. A. Dahl Effect of anxiety and depression on blood pressure: 11-year longitudinal population study The British Journal of Psychiatry, August 1, 2008; 193(2): 108 - 113. [Abstract] [Full Text] [PDF]

				B. Hildrum, A. Mykletun, E. Stordal, I. Bjelland, A. A Dahl, and J. Holmen Association of low blood pressure with anxiety and depression: the Nord-Trondelag Health Study J. Epidemiol. Community Health, January 1, 2007; 61(1): 53 - 58. [Abstract] [Full Text] [PDF]

				M. BOBAK, H. PIKHART, A. PAJAK, R. KUBINOVA, S. MALYUTINA, H. SEBAKOVA, R. TOPOR-MADRY, Y. NIKITIN, and M. MARMOT Depressive symptoms in urban population samples in Russia, Poland and the Czech Republic The British Journal of Psychiatry, April 1, 2006; 188(4): 359 - 365. [Abstract] [Full Text] [PDF]

				J. Cervilla, M. Prince, S. Joels, C. Russ, and S. Lovestone Genes Related to Vascular Disease (APOE, VLDL-R, DCP-1) and Other Vascular Factors in Late-Life Depression Am J Geriatr Psychiatry, April 1, 2004; 12(2): 202 - 210. [Abstract] [Full Text] [PDF]

				B. A. Golomb, M. H. Criqui, H. White, and J. E. Dimsdale Conceptual Foundations of the UCSD Statin Study: A Randomized Controlled Trial Assessing the Impact of Statins on Cognition, Behavior, and Biochemistry Arch Intern Med, January 26, 2004; 164(2): 153 - 162. [Abstract] [Full Text] [PDF]

				M. G. Cole and N. Dendukuri Risk Factors for Depression Among Elderly Community Subjects: A Systematic Review and Meta-Analysis Am J Psychiatry, June 1, 2003; 160(6): 1147 - 1156. [Abstract] [Full Text] [PDF]

				A. F. JORM Association of hypotension with positive and negative affect and depressive symptoms in the elderly The British Journal of Psychiatry, June 1, 2001; 178(6): 553 - 555. [Abstract] [Full Text] [PDF]

				R. STEWART, M. PRINCE, A. MANN, M. RICHARDS, and C. BRAYNE Stroke, vascular risk factors and depression: Cross-sectional study in a UK Caribbean-born population The British Journal of Psychiatry, January 1, 2001; 178(1): 23 - 28. [Abstract] [Full Text] [PDF]

				R. Stewart Low blood pressure and depression in the elderly The British Journal of Psychiatry, August 1, 2000; 177 (2): 181b - 182b. [Full Text] [PDF]