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The British Journal of Psychiatry (2000) 177: 38-41
© 2000 The Royal College of Psychiatrists

Schizophrenia is not disappearing in south-west Scotland

J. ALLARDYCE, MRCPsych, G. MORRISON, MRCPsych and R. G. McCREADIE, FRCPsych

Department of Clinical Research, Crichton Royal Hospital, Dumfries

J. VAN OS, PhD

European School of Neurosciences, Maastricht University, The Netherlands

J. KELLY, MRCP and R. M. MURRAY, FRCPsych

Institute of Psychiatry, London

Correspondence: Dr J. Allardyce, Department of Clinical Research, Crichton Royal Hospital, Dumfries DGI 4TG, Scotland, UK. Tel : +44 1387 244000 ; Fax : +44 1387 257735 ; e-mail : j.allardyce{at}clinmed.gla.ac.uk

Declaration of interest This work was supported by the Stanley Foundation.

Background Recent work has reported a decline in the incidence of schizophrenia, but it is unclear if these findings reflect a true decrease in its incidence or are an artefact arising from methodological difficulties.

Aims To take account of these methodological difficulties and report service-based incidence rates for schizophrenia in Dumfries and Galloway in south-west Scotland for 1979-98.

Method Using both clinical diagnoses and diagnoses generated from the Operational Checklist for Psychotic Disorders (OPCRIT) computer algorithm for ICD—10 and DSM-IV schizophrenia, we measured change in the incidence rates over time. We used indirect standardisation techniques and Poisson models to measure the rate ratio linear trend.

Results There was a monotonic and statistically significant decline in clinically diagnosed schizophrenia. The summary rate ratio linear trend was 0.77. However using OPCRIT-generated ICD—10 and DSM-IV diagnoses, there was no significant difference over time.

Conclusions OPCRIT-generated consistent diagnoses revealed no significant fall in the incidence of schizophrenia. Changes in diagnostic practice have caused the declining rates of clinically diagnosed schizophrenia in Dumfries and Galloway.




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