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Quality of life in schizophrenia: development, reliability and internal consistency of the Lancashire Quality of Life Profile - European Version

EPSILON Study 8

Clinical and Social Psychiatry Research Unit, University of Cantabria, Santander, Spain

AART H. SCHENE, MD

Department of Psychiatry, Academic Medical Centre, Amsterdam, The Netherlands

BIRGITTE WELCHER, MD

Hvidovre Hospital, Department of Psychiatry, Copenhagen, Denmark

GRAHAM THORNICROFT, MRCPsych and MORVEN LEESE, PhD

Section of Community Psychiatry (PRiSM), Institute of Psychiatry, King's College, London, UK

MIRELLA RUGGERI, MD

Department of Medicine and Public Health, Section & Psychiatry, University of Verona, Italy

EPSILON STUDY GROUP

Correspondence: Professor José Luis Vázquez-Barquero, Professor of Psychiatry, Unidad de Investigación en Psiquiatria Clinica y Social, Hospital Universitario ‘Marqués de Valdecilla’, Universidad de Cantabria, Avda. Valdecilla s/n, 39008 Santander, Spain. Tel: +34 942 203 446 or 202 545; fax: +34 942 202 655 or 203 447

Declaration of interest No conflict of interest. Funding detailed in Acknowledgements.

Background This paper, part of the European Psychiatric Services: Inputs Linked to Outcome Domains and Needs (EPSILON) Study, reports the development, reliability and internal consistency of the Lancashire Quality of Life Profile - European Version (LQoLP-EU) in a representative sample of people with schizophrenia from five European sites.

Method The LQoLP-EU was administered to a total sample of 404 patients to check its internal consistency, and a sub-sample of 294 patients was interviewed a second time within 7-15 days to verify its test-retest reliability.

Results Internal consistency of the total domains, perceived QoL scale (Life Satisfaction Scale, LSS) was good at 0.87. Of the nine subjective QoL domains Work and Leisure showed the lowest internal consistency (0.30 and 0.56 respectively), the values of the remaining sub-scales ranging between 0.62 and 0.88. The pooled ICC score for LSS was 0.82, and for the nine subjective QoL domain subscales it ranged from 0.61 (Safety) to 0.75 (Living Situation). There were significant differences between the sites in and ICCs for sub-scales, but not for the LSS.

Conclusion The LQoLP-EU has good internal consistency and reliability in the five European centres.

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