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The British Journal of Psychiatry (2000) 177: 360-365
© 2000 The Royal College of Psychiatrists

Psychosocial and psychiatric risk factors for suicide

Case—control psychological autopsy study*

ANDREW T. A. CHENG, FRCPsych

Division of Epidemiology, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan

TONY H. H. CHEN, PhD

Institute of Epidemiology, College of Public Health, National Taiwan University, Taipei, Taiwan

CHWEN-CHEN CHEN, MRCPsych

Department of Psychiatry, National Cheng Kung University, Tainan, Taiwan

RACHEL JENKINS, FRCPsych, Director of WHO Collaborating Centre

Institute of Psychiatry, King's College London, UK

Correspondence: Professor Andrew T. A. Cheng, Division of Epidemiology, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan. Fax: +886 2 2785 3569; e-mail: bmandrew{at}ccvax.sinica.edu.tw

Declaration of interest The work was supported by a grant from the National Science Council, Taiwan (NSC79-0301-H002-04/NSC80-0301-H002-07).

* Presented in part at the XIX Congress of the International Association for Suicide Prevention, Adelaide, 17 April 1997, and the XVI Congress of the World Association for Social Psychiatry, Vancouver, BC, 20 August 1988.

Background Few studies of suicide have simultaneously examined the individual and combined effects of psychosocial and psychiatric risk factors.

Aims To do so in a representative sample of suicides.

Method A case—control psychological autopsy was conducted among 113 consecutive suicides and 226 living controls matched for age, gender, ethnicity and area of residence in Taiwan.

Results Five major risk factors (loss event, suicidal behaviour in first-degree relatives, ICD-10 major depressive episode, emotionally unstable personality disorder and substance dependence) were found to have independent effects on suicide from multivariate conditional logistic regression analysis.

Conclusions Effective intervention and management for loss event and major depressive episode among emotionally unstable subjects with a family tendency of suicidal behaviour, frequently also comorbid with alcohol or other substance dependence, may prove to be most effective for suicide prevention in different populations.




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