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The British Journal of Psychiatry (2001) 178: 166-171
© 2001 The Royal College of Psychiatrists

Intellectual functioning and outcome of patients with severe psychotic illness randomised to intensive case management

Report from the UK700 trial

A. HASSIOTIS, MRCPsych

Department of Psychiatry and Behavioural Sciences, RF & UCMS, London

O.C. UKOUMUNNE, MSc

Department of Medical Statistics and Evaluation, Imperial College School of Medicine, London

S. BYFORD, MSc

Centre for Health Economics, University of York, York

P. TYRER, FRCPsych

Department of Public Mental Health, London

K. HARVEY, BA

Department of Psychiatry, St George's Hospital Medical School, London

J. PIACHAUD, MRCPsych

Harperbury Hospital, Radlett, Hertfordshire

K. GILVARRY, BSc

Brixton Community Care Project, Maudsley Hospital, London

J. FRASER, BA

Mental Illness Research Unit, University of Manchester, Manchester

Correspondence: Dr A. Hassiotis, Department of Psychiatry and Behavioural Sciences, Royal Free and University College Medical School, Wolfson Building, 48 Riding House Street, London WIN 8AA, UK. Tel: 020 7504 9451; fax: 020 7323 1459; e-mail: a.hassiotis{at}ucl.ac.uk

Declaration of interest Funded by the Department of Health Research and Development Programme.

Background Little research has been carried out on the benefits of intensive case management (ICM) for people with borderline IQ and severe mental illness.

Aims To compare outcome and costs of care of patients with severe psychotic illness with borderline IQ to patients of normal IQ and to assess whether ICM is more beneficial for the former than for the latter.

Method The study utilises data from the UK700 multi-centre randomised controlled trial of case management. The main outcome measure was the number of days spent in hospital for psychiatric reasons. Secondary outcomes were costs of care and clinical outcome.

Results ICM was significantly more beneficial for borderline-IQ patients than those of normal IQ in terms of reductions in days spent in hospital, hospital admissions, total costs and needs and increased satisfaction.

Conclusions ICM appears to be a cost-effective strategy for a subgroup of patients with severe psychosis with cognitive deficits.




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