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The British Journal of Psychiatry (2001) 178: 420-426
© 2001 The Royal College of Psychiatrists

Predictors of later schizophrenia and affective psychosis among attendees at a child psychiatry department{dagger}

MARY CANNON, MRCPsych and ELIZABETH WALSH, MRCPsych

Division of Psychological Medicine, Institute of Psychiatry, London

CHRISTOPHER HOLLIS, MRCPsych

Section of Developmental Psychiatry, University of Nottingham, Nottingham

MARESC KARGIN, MRCPsych

Division of Psychological Medicine, Institute of Psychiatry, London

ERIC TAYLOR, FRCPsych

Department of Child and Adolescent Psychiatry, Institute of Psychiatry, London

ROBIN M. MURRAY, FRCPsych

Division of Psychological Medicine, Institute of Psychiatry, London

PETER B. JONES, MRCPsych

Department of Psychiatry, University of Cambridge.

Correspondence: Dr Mary Cannon, Division of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London SE5 8AF, UK. E-mail: m.cannon{at}iop.kcl.ac.uk

Declaration of interest None. Funding detailed in Acknowledgements.

{dagger} See editorial, pp. 395–396, this issue.

Background Schizophrenia has been linked with psychological problems in childhood but there is little information on precursors of affective psychosis.

Aims To compare childhood psychological antecedents of adult schizophrenia and affective psychosis.

Method Childhood item sheets, which give standardised information on signs and symptoms of mental illness in the year preceding assessment are completed for all attendees at the children's department of the Maudsley and Bethlem Royal Hospital. We examined item sheet data on individuals with an adult diagnosis of schizophrenia (n=59) or affective psychosis (n=27) and a comparison group with no adult mental illness (n=86) (all had attended the department).

Results Abnormal suspiciousness or sensitivity and relationship difficulties with peers are associated with later schizophrenia. In contrast, affective psychosis is associated with childhood hysterical symptoms and disturbances in eating.

Conclusions Childhood psychological precursors for schizophrenia and affective psychosis differ and do not simply reflect non-specific psychiatric disturbance in adolescence.


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