Department of Psychiatry, University of Newcastle-upon-Tyne, Royal Victoria Infirmary, Newcastle-upon-Tyne
Department of Psychiatry, University of Southampton, Royal South Hampshire Hospital, Southampton
Department of Psychiatry, Homerton Hospital, London
Correspondence: D. Turkington, Department of Psychiatry, University of Newcastle-upon-Tyne, Royal Victoria Infirmary, Queen Victoria Rd, Newcastle-upon-Tyne NEI 4LP, UK. Tel: 0191 282 4842; e-mail: douglas.turkington{at}ncl.ac.uk
Declaration of interest Funding was provided by Pfizer Ltd.
Background Little evidence exists to indicate whether community psychiatric nurses can achieve the results reported by expert cognitivebehavioural therapists in patients with schizophrenia.
Aims To assess the effectiveness and safety of a brief cognitivebehavioural therapy (CBT) intervention in a representative community sample of patients with schizophrenia in secondary care settings.
Method A pragmatic randomised trial was performed involving 422 patients and carers to compare a brief CBT intervention against treatment as usual.
Results Patients who received CBT (n=257) improved in overall symptomatology (P=0.015; number needed to treat [NNT]=13), insight (P<0.001; NNT=10) and depression (P=0.003; NNT=9) compared with the controlgroup (n=165). Insight was clinically significantly improved (risk ratio=1.15, 95% CI 1.01-1.31). There was no increase in suicidal ideation.
Conclusions Community psychiatric nurses can safely and effectively deliver a brief CBT intervention to patients with schizophrenia and their carers.
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