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The British Journal of Psychiatry (2003) 182: 20-30
© 2003 The Royal College of Psychiatrists

Impact of the ICD-10 Primary Health Care (PHC) diagnostic and management guidelines for mental disorders on detection and outcome in primary care

Cluster randomised controlled trial{dagger}

TIM CROUDACE, PhD

Department of Psychiatry University of Cambridge, UK

JONATHAN EVANS, MRCPsych and GLYNN HARRISON, FRCPsych

Division of Psychiatry, University of Bristol, UK

DEBORAH J. SHARP, FRCGP

Division of Primary Health Care, University of Bristol, UK

ELLEN WILKINSON, MRCPsych, GEMMA McCANN, BA, MATHEW SPENCE, BSc, CATHERINE CRILLY, MRCGP and LUCY BRINDLE, BSc

Division of Psychiatry, University of Bristol, UK

Correspondence: Tim Croudace, Department of Psychiatry, University of Cambridge, Box 189, Addenbrooke's Hospital, Cambridge CB2 2QQ, UK

Declaration of interest D.J.S. was involved in the development of the WHO guidelines.

{dagger} See editorial, pp. 1–2, this issue.

Background The World Health Organization (WHO) ICD-10 Primary Health Care (PHC) Guidelines for Diagnosis and Management of Mental Disorders (1996) have not been evaluated in a pragmatic randomised controlled trial (RCT).

Aims To evaluate the effect of local adaptation and dissemination of the guidelines.

Method Pragmatic, pair-matched, cluster RCT involving 30 practices.

Results Guideline practices were less sensitive but more specific in identifying morbidity, but these differences were not significant. Guideline patients did not differ from usual-care patients on 12-item General Health Questionnaire scores at 3-month follow-up or in the proportion who were still cases. There were no significant differences in secondary outcomes.

Conclusions Attempts to influence clinician behaviour through a process of adaptation and extension of guidelines are unlikely to change detection rates or outcomes.


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