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The British Journal of Psychiatry (2003) 182: 45-49
© 2003 The Royal College of Psychiatrists

Incidence of schizophrenia in south-east London between 1965 and 1997

J. BOYDELL, MRCPsych

Institute of Psychiatry, London, UK

J. VAN OS, MRCPsych

European Graduate School of Neuroscience, Maastricht University, The Netherlands, and Institute of Psychiatry, London, UK

M. LAMBRI, MSc

Institute of Psychiatry, London, UK

D. CASTLE, MRCPsych

University of Western Australia, Perth, Australia

J. ALLARDYCE, MRCPsych and R. G. McCREADIE, FRCPsych

Crichton Royal Hospital, Dumfries, UK

R. M. MURRAY, FRCPsych

Institute of Psychiatry, London, UK

Correspondence: Dr. J. Boydell, Division of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London SE5 8AF, UK. Tel: 020 7848 0260; e-mail: j.boydell{at}iop.kcl.ac.uk

Declaration of interest None.

Funding detailed in Acknowledgements.

Background There has been much debate about changes in the incidence of schizophrenia.

Aims To identify any changes in incidence of schizophrenia in Camberwell, south-east London, between 1965 and 1997.

Method Research Diagnostic Criteria and DSM—III—R diagnoses were generated for all first contacts by the OPCRIT computer program, and incidence rates of schizophrenia in seven time periods were measured. Indirect standardisation and Poisson models were used to measure the effect of time period and to examine interactions with age and gender.

Results There was a continuous and statistically significant increase in the incidence of schizophrenia, which was greatest in people under 35 years of age and was not gender-specific.

Conclusions The incidence of schizophrenia has doubled in south-east London over the past three decades.


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