© 2003 The Royal College of Psychiatrists
Mild cognitive impairment: prevalence and incidence according to different diagnostic criteria
Results of the Leipzig Longitudinal Study of the Aged (LEILA75+)
Department of Psychiatry, University of Leipzig, Germany
Correspondence: Anja Busse, Department of Psychiatry, University of Leipzig, Johannisallee 20, D-04317 Leipzig, Germany. Tel: +493419724530; fax: +493419724539; e-mail: krausem{at}medizin.uni-leipzig.de
Declaration of interest The study was supported by the
Interdisciplinary Centre for Clinical Research, University of Leipzig (JZKF,
IKS9504, Project C7_79934700).
Background Although mild cognitive impairment is associated with an increased risk of developing dementia, there has been little work on its incidence and prevalence.
Aims To report age-specific prevalence, incidence and predictive validities for four diagnostic concepts of mild cognitive impairment.
Method A community sample of 1045 dementia-free individuals aged 75 years and over was examined by neuropsychological testing in a three-wave longitudinal study.
Results Prevalence rates ranged from 3% to 20%, depending on the concept applied. The annual incidence rates applying different case definitions varied from 8 to 77 per 1000 person-years. Rates of conversion to dementia over 2.6 years ranged from 23% to 47%.
Conclusions Mild cognitive impairment is frequent in older people. Prevalence, incidence and predictive validities are highly dependent on the diagnostic criteria applied.
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