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The British Journal of Psychiatry (2004) 184: 357-358
© 2004 The Royal College of Psychiatrists

SHORT REPORTS

Spontaneous improvement in severe, chronic schizophrenia and its neuropsychological correlates

G. K. MURRAY, MRCPsych

Department of Psychiatry, University of Cambridge, Addenbrooke’s Hospital, Cambridge, and Department of Psychiatry, University of Oulu, Finland

V. LEESON, PhD

Department of Psychology, London Metropolitan University, London

P. J. MCKENNA, MRCPsych

Fulbourn Hospital, Cambridge

Correspondence: P. J. McKenna, Fulbourn Hospital, Cambridge CB1 5EF, UK

Declaration of interest None.

ABSTRACT

Cognitive impairment is well established in schizophrenia but its relationship to the course of the illness remains incompletely understood. Here we document two patients with schizophrenia who underwent neuropsychological testing while chronically unwell, and this was repeated after improvement took place. Both patients showed significant recovery of general intellectual function, accompanied by improvements in some but not all areas of neuropsychological function: executive function remained particularly impaired.


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