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The British Journal of Psychiatry (2004) 184: 386-392
© 2004 The Royal College of Psychiatrists

Global burden of depressive disorders in the year 2000{dagger}

T. B. Üstün, MD MRCP

Global Programme on Evidence for Health Policy, WHO

J. L. Ayuso-Mateos, MD

Department of Psychiatry, Universidad Autónoma de Madrid, Spain

S. Chatterji, MD, C. Mathers, PhD and C. J. L. Murray, MD DPhil

Global Programme on Evidence for Health Policy, WHO

Correspondence: T. B. Üstün, Classification, Assessment, Surveys and Terminology Team, World Health Organization, Avenue Appia 20, CH-1211, Geneva 27, Switzerland. Tel: +41 22 7913609; fax: +41 22 7914885/4160; e-mail: ustunb{at}who.int

Declaration of interest None.

{dagger} See pp. 393–403 and editorial, pp. 379–380, this issue.

Background The initial Global Burden of Disease study found that depression was the fourth leading cause of disease burden, accounting for 3.7% of total disability adjusted life years (DALYs) in the world in 1990.

Aims To presentthe new estimates of depression burden for the year 2000.

Method DALYs for depressive disorders in each world region were calculated, based on new estimates of mortality, prevalence, incidence, average age at onset, duration and disability severity.

Results Depression is the fourth leading cause of disease burden, accounting for 4.4% of total DALYs in the year 2000, and it causes the largest amount of non-fatal burden, accounting for almost 12% of all total years lived with disability worldwide.

Conclusions These data on the burden of depression worldwide represent a major public health problem that affects patients and society.


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Depression: international intervention for a global problem
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BJP 2004 184: 379-380. [Full Text]  

Highlights of this issue

BJP 2004 184: 379-a19. [Full Text]  

Reducing the global burden of depression: Population-level analysis of intervention cost-effectiveness in 14 world regions
Dan Chisholm, Kristy Sanderson, Jose Luis Ayuso-Mateos, and Shekhar Saxena
BJP 2004 184: 393-403. [Abstract] [Full Text]  

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BJP 2004 184: 464. [Full Text]  



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