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The British Journal of Psychiatry (2006) 188: 231-236. doi: 10.1192/bjp.188.3.231
© 2006 The Royal College of Psychiatrists
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Alcohol consumption and suicide among middle-aged men in Japan

TATSUO AKECHI, MD, PhD

Department of Psychiatry, Nagoya City University Medical School, Nagoya and Psycho-Oncology Division, National Cancer Centre Research Institute East, Chiba

MOTOKI IWASAKI, MD, PhD

Epidemiology and Prevention Division, Research Centre for Cancer Prevention and Screening, National Cancer Centre, Tokyo

YOSUKE UCHITOMI, MD, PhD

Psycho-Oncology Division, National Cancer Centre Research Institute East, Chiba

SHOICHIRO TSUGANE, MD, PhD JPHC Study Group

Epidemiology and Prevention Division, Research Centre for Cancer Prevention and Screening, National Cancer Centre, Tokyo, Japan

Correspondence: Dr Shoichiro Tsugane, Epidemiology and Prevention Division, Research Centre for Cancer Prevention and Screening, National Cancer Centre, 5 -1-1Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.Tel: +81 3 3542 2511 extension 3385; Fax: +81 3 3547 8578; e-mail: stsugane{at}ncc.go.jp

Declaration of interest None. Funding detailed in Acknowledgements.

Background Few studies have investigated large population-based cohorts for an association between alcohol consumption and suicide.

Aims To investigate the possible association between alcohol intake and suicide.

Method We used nationwide population-based cohortdata from the Japan Public Health Centre-Based Prospective Study cohort. Atotal of 43 383 men aged 40–69 years participated. Death from suicide was defined according to ICD–10 as codes X60–X84.

Results During the 367817 person-years of follow-up, there were168 suicides. Compared with occasional drinkers, the pooled multivariate relative risk (RR; with 95% CI) of suicide for non-drinkers and regular heavy drinkers was 2.3 (1.2–4.6) and 2.3 (1.2–4.7) respectively. The RR increased with the amount of alcohol consumed (P for trend=0.004).

Conclusions There is a U-shaped association between alcohol consumption and subsequent suicide.


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Among middle aged men in Japan, non-drinkers and regular heavy drinkers are more likely to commit suicide than occasional drinkers.
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