The British Journal of Psychiatry (2007) 190: 1-3. doi: 10.1192/bjp.bp.106.027003
© 2007 The Royal College of Psychiatrists
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EDITORIALS

Gene–environment interplay in attention-deficit hyperactivity disorder and the importance of a developmental perspective

ANITA THAPAR, FRCPsych and KATE LANGLEY, PhD

Department of Psychological Medicine, Cardiff University, Cardiff

PHILIP ASHERSON, FRCPsych

Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, London, UK

MICHAEL GILL, MD, MRCPsych

School of Medicine and Health Sciences, Trinity College, Dublin, Ireland

Correspondence: Professor Anita Thapar, Child and Adolescent Psychiatry Section, Department of Psychological Medicine, Cardiff University School of Medicine, Heath Park, Cardiff CF14 4XN, UK. Email: thapar{at}cf.ac.uk

Declaration of interest None.

Attention-deficit hyperactivity disorder (ADHD) varies in its clinical presentation and course. Susceptibility gene variants for ADHD and associated antisocial behaviour are being identified with emerging evidence of gene–environment interaction. Genes and environmental factors that influence the origins of disorder are not necessarily the same as those that contribute to its course and outcome.


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