The British Journal of Psychiatry (2007) 190: 57-62. doi: 10.1192/bjp.bp.106.022954
© 2007 The Royal College of Psychiatrists
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Competition for neuronal resources: how hallucinations make themselves heard

DANIELA HUBL, MD, THOMAS KOENIG, PhD and WERNER K. STRIK, MD

Department of Psychiatric Neurophysiology, University Hospital of Psychiatry, Bern, Switzerland

LESTER MELIE GARCIA, PhD

Cuban Neuroscience Centre, Havana, Cuba

THOMAS DIERKS, MD

Department of Psychiatric Neurophysiology, University Hospital of Psychiatry, Bern, Switzerland

Correspondence: Daniela Hubl, University Hospital of Psychiatry, Department of Psychiatric Neurophysiology, Bolligenstrasse 111, CH-3000 Bern 60, Switzerland. Tel: +41 31 930 95 22; fax: +4131 930 99 61; email: hubl{at}puk.unibe.ch

Declaration of interest None. Funding detailed in Acknowledgements.

Background Hallucinations are perceptions in the absence of a corresponding external sensory stimulus. However, during auditory verbal hallucinations, activation of the primary auditory cortex has been described.

Aims The objective of this study was to investigate whether this activation of the auditory cortex contributes essentially to the character of hallucinations and attributes them to alien sources, or whether the auditory activation is a sign of increased general auditory attention to external sounds.

Method The responsiveness of the auditory cortex was investigated by auditory evoked potentials (N100) during the simultaneous occurrence of hallucinations and external stimuli. Evoked potentials were computed separately for periods with and without hallucinations; N100 power, topography and brain electrical sources were analysed.

Results Hallucinations lowered the N100 amplitudes and changed the topography, presumably due to a reduced left temporal responsivity.

Conclusions This finding indicates competition between auditory stimuli and hallucinations for physiological resources in the primary auditory cortex. The abnormal activation of the primary auditory cortex may thus be a constituent of auditory hallucinations.


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