The British Journal of Psychiatry (2007) 190: 237-242. doi: 10.1192/bjp.bp.106.025155
© 2007 The Royal College of Psychiatrists
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Mortality in people with schizophrenia in rural China

10-year cohort study

Mao-Sheng Ran, MD, PhD

Hong Kong Jockey Club Centre for Suicide Research and Prevention, University of Hong Kong, China, College of Professional Studies, University of Guam, USA, and Institute of Mental Health, West China Medical School of Sichuan University, Chengdu, China

Eric Yu-Hai Chen, MD

Hong Kong Jockey Club Centre for Suicide Research and Prevention, Universisty of Hong Kong, China

Yeates Conwell, MD

Department of Psychiatry, University of Rochester Medical Center, Rochester, New York, USA

Cecilia Lai-Wan Chan, PhD and Paul S. F. Yip, PhD

Hong Kong Jockey Club Centre for Suicide Research and Prevention, University of Hong Kong

Meng-Ze Xiang, MD

Institute of Mental Health, West China Medical School of Sichuan University, Chengdu, China

Eric D. Caine, MD

Department of Psychiatry, University of Rochester Medical Center, Rochester, New York, USA

Correspondence: Dr Mao-Sheng Ran, College of Professional Studies, University of Guam, Mangilao, Guam 96923, USA. Tel: +1 671 735 2655; fax: +1 671 734 1203; email: ranmaosh{at}yahoo.com

Declaration of interest None.

Funding detailed in Acknowledgements.

Background Long-term mortality and the risk factors for premature death among patients with schizophrenia living in rural communities are unknown.

Aims To explore the 10-year mortality and its risk factors among patients with schizophrenia.

Method We used data from a 10-year prospective follow-up study (1994–2004) of mortality among people with schizophrenia, and death registration data for Xinjin County, Chengdu, China.

Results The mortality rate was 2228 per 100 000 person-years during follow-up. Both all-cause mortality and suicide rates were significantly greater in male than in female patients. Age at illness onset (>45 years), duration of illness (>=10 years), age greater than 50 years, physical illness, in ability to work, male gender, and never having received treatment were identified as independent predictors of increased mortality.

Conclusions Higher mortality rates in male patients may contribute to the higher prevalence of schizophrenia in women compared with men in China. The findings of risk factors for mortality should be taken into account when developing interventions to improve outcomes among people with schizophrenia.


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