The British Journal of Psychiatry (2007) 190: 533-534. doi: 10.1192/bjp.bp.106.028019
© 2007 The Royal College of Psychiatrists
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SHORT REPORTS

Adjunctive fast repetitive transcranial magnetic stimulation in depression

IAN M. ANDERSON, MD, MRCP, FRCPsych and NICOLA A. DELVAI, DipLaurMedCh

Neuroscience and Psychiatry Unit, University of Manchester

BETTADAPURA ASHIM, MSc, MRCPsych

Merseycare NHS Trust

SINDHU ASHIM, MSc, MRCPsych

The Spinney, Partnerships in Care, Atherton, Manchester

CHERRY LEWIN, MRCPsych, VINEET SINGH, MRCPsych, DANIEL STURMAN, MRCPsych and PAUL L. STRICKLAND, PhD, MRCPsych

Bolton, Salford & Trafford Mental Health NHS Trust, UK

Correspondence: Correspondence: Dr Ian Anderson, Neuroscience and Psychiatry Unit, Room G907, Stopford Building, Oxford Road, Manchester M13 9PT, UK. Tel: +44 (0)161 275 7428; fax: +44 (0)161 275 7429; email: ian.anderson{at}manchester.ac.uk

Declaration of interest None.

The place of repetitive transcranial magnetic stimulation (rTMS) in the treatment of depression remains unclear. In this sham-controlled study we determined the efficacy and acceptability offast, left frontal rTMS given three times a week over 4–6 weeks to 29 patients with depression (79% treatment-resistant). The procedure was generally well tolerated and more effective than sham treatment (55 v.77% responding, P<0.05), with improvement maintained to 12 weeks. This therapy could be a useful addition to available treatments but further research is needed to determine the optimum treatment parameters.


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