The British Journal of Psychiatry (2008) 193: 254-255. doi: 10.1192/bjp.bp.107.045922
© 2008 The Royal College of Psychiatrists
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SHORT REPORT

Verbal memory and treatment response in post-traumatic stress disorder

Jennifer Wild, DClinPsy

Institute of Psychiatry, King’s College London, UK

Ruben C. Gur, PhD

Neuropsychiatry Section, Department of Psychiatry, University of Pennsylvania School of Medicine, and the Philadelphia Veterans Administration Hospital, Polytrauma Unit, Philadelphia, USA

Correspondence: Dr Jennifer Wild, King’s College London, Department of Psychology (PO77), Institute of Psychiatry, De Crespigny Park, Denmark Hill, London SE5 8AF, UK. Email: j.wild{at}iop.kcl.ac.uk

Declaration of interest

None.

Post-traumatic stress disorder (PTSD) is often associated with verbal memory deficits, which could influence treatment outcome. We assessed neuropsychological functioning in individuals with PTSD and their response to cognitive–behavioural therapy (CBT). Treatment non-responders had significantly poorer performance on measures of verbal memory compared with responders and demonstrated narrative encoding deficits. Differences were not explained by IQ, performance on tasks of attention, initial PTSD severity, depression, time since trauma, or alcohol/substance misuse. Verbal memory deficits seem to diminish the effectiveness of CBT and should be considered in its implementation.


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