Department of Clinical Psychology, University of Leeds
Department of Psychiatry, University of Nottingham
Postgraduate Statistics Centre, Department of Mathematics and Statistics, University of Lancaster
Department of Clinical Psychology, University of Liverpool
School of Psychology, University of Bangor, Gwynedd, UK
Correspondence: Richard P. Bentall, School of Psychology, Adeilad Brigantia, University of Bangor, Gwynedd LL57 2AS, UK. Email: richard.bentall{at}bangor.ac.uk
None. Funding detailed in Acknowledgements.
Background
Psychological processes in bipolar disorder are of both clinical and theoretical importance.
Aims
To examine depressogenic psychological processes and reward responsivity in relation to different mood episodes (mania, depression, remission) and bipolar symptomatology.
Method
One hundred and seven individuals with bipolar disorder (34 in a manic/hypomanic or mixed affective state; 30 in a depressed state and 43 who were euthymic) and 41 healthy controls were interviewed with Structured Clinical Interview for DSM–IV and completed a battery of self-rated and experimental measures assessing negative cognitive styles, coping response to negative affect, self-esteem stability and reward responsiveness.
Results
Individuals in all episodes differed from controls on most depression-related and reward responsivity measures. However, correlational analyses revealed clear relationships between negative cognitive styles and depressive symptoms, and reward responsivity and manic symptoms.
Conclusions
Separate psychological processes are implicated in depression and mania, but cognitive vulnerability to depression is evident even in patients who are euthymic.
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