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Journal of Mental Science (1950) 96: 1037-1042. doi: 10.1192/bjp.96.405.1037
© 1950 The Royal College of Psychiatrists
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A Comparison of Desoxyephedrine (Methedrine), and Electroshock in the Treatment of Depression

A. B. Monro, M.D., D.P.M. and H. Conitzer, M.D., Ph.D.

Carlton Hayes Hospital, Narborough, Leicester

ABSTRACT

  1. A description is given of an enquiry into the treatment of depressed patients by desoxyephedrine.
  2. A control series of 200 patients treated by electroshock is analyzed to elucidate those factors associated with good results from the treatment.
  3. From this analysis four prognostic categories are derived, and the results to be expected in each from treatment by electroshock are tabulated.
  4. The results in 34 cases treated by desoxyephedrine are tabulated in a similar manner.
  5. It is shown that in the first three of these categories the results from electroshock are better than those from desoxyephedrine.
  6. Attention is drawn to the fact that in the fourth category, where electroshock is poorly indicated, the results from desoxyephedrine are relatively better.
  7. It is suggested that it might be worth while investigating further the possible value of desoxyephedrine in depressed cases which do not respond well to electroshock.

Received for publication July 2, 1950.





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Psychiatric Bulletin Advances in Psychiatric Treatment All RCPsych Journals
Copyright © 1950 The Royal College of Psychiatrists.