The British Journal of Psychiatry (2006) 188: 81-82. doi: 10.1192/bjp.bp.105.011221
© 2006 The Royal College of Psychiatrists
The 10/90 divide in mental health research: trends over a 10-year period
SHEKHAR SAXENA, MD, MRCPsych
Mental Health: Evidence and Research, Department of Mental Health and
Substance Abuse, World Health Organization, Geneva, Switzerland
GUILLERMO PARAJE, DPhil
Equity in Health Group, World Health Organization, Geneva,
Switzerland
PRATAP SHARAN, MD, PhD
Mental Health: Evidence and Research, Department of Mental Health and
Substance Abuse, World Health Organization, Geneva, Switzerland
GHASSAN KARAM, BSc
Health Research Systems Analysis, Department of Research Policy and
Cooperation, World Health Organization, Geneva, Switzerland
RITU SADANA, MSPH, DS
Health Research Systems Analysis, Evidence for Information and Policy
Cluster, World Health Organization, Geneva, Switzerland
Correspondence:
Dr Shekhar Saxena, Coordinator, Mental Health: Evidence and Research,
Department of Mental Health and Substance Abuse, World Health Organization,
CH-1211, Geneva, Switzerland. Fax +41 22 7914160; e-mail:
saxenas{at}who.int
Declaration of interest None.

ABSTRACT
Summary A search (precision value 94%, recall value 93%) of
the ISI
Web of Science database (1992-2001) revealed that mental
health publications
accounted for 3-4% of the health literature.
A 10/90 divide in internationally
accessible mental health
literature was evident and remained undiminished
through 10
years as low- and middle-income countries (
n=152)
contributed
only 6%, high-income countries (
n=54) 94%, and 14 leading
high-income
countries (with more than 1% contribution for majority of years
under consideration) contributed 90% of internationally accessible
mental
health research. Steps should be taken to improve the
research infrastructure
and capacity to conduct and disseminate
mental health research in general, and
on a priority basis
in low- and middle-income countries.

INTRODUCTION
Health research plays a major role in advancing science and
in providing
solutions for health problems. Imbalances in health
research output in terms
of populations and disease burden
addressed have been noted
(
Horton, 2003;
Canadian Medical Association Journal,
2004;
Rochon et al,
2004;
Paraje et al,
2005) and aptly labelled Western medical journals and
the
10/90 problem (
Canadian Medical
Association Journal, 2004).
In comparison with the burden imposed
by mental disorders
(13% of global burden of diseases), mental health is an
underresearched
health area. In a study on global significance of health
research
by Rochon
et al
(
2004), only 2.44% of clinical
trials on 25
leading contributors to global burden of diseases targeted mental
disorders. Geographical disproportions have also been recorded
and commented
upon in mental health research; only about 6%
(or less) of publications are
from low- and middle-income countries
(
Patel & Sumathipala, 2001;
Parker & Parker, 2002;
Saxena et al, 2004;
Tyrer, 2005). Here we examine
mental
health literature within internationally accessible health literature
for geographical distribution over a 10-year period.

METHOD
The 4061 health-related journals indexed in the ISI Web of Science
database
(1992-2001) were searched for all publications on
mental health, mental
disorders and services for mental health.
The ISI database does not
exhaustively list internationally
accessible literature but its listing of
institutional affiliation
of all authors, a feature that is not offered by
other databases
(including Medline), which list the affiliation of only one
author, makes it uniquely suited for assessment of geographical
contribution
to publications.
The list of keywords included global terms such as behaviour, psychology,
psychiatry, psychosocial, mental health, mental disorders, mental development,
intellectual disability; specific terms such as organic brain syndrome,
dementia, drug abuse, psychosis, schizophrenia; and service-related terms such
as mental healthcare, psychiatric hospital, psychiatric services, halfway
home, residential psychiatric care, and community mental health. (Complete
list available from authors on request.) The final set of keywords was
selected by an iterative process that yielded a precision value of 94% and
recall value of 93% (precision: proportion of relevant articles among those
retrieved; recall: proportion of articles in a random sample of mental health
journals that were retrieved by the search strategy).
The countries of origin for each publication were determined by the
fractional counting method (assigning an equal fraction of each publication to
all listed countries).

RESULTS
Out of 3 288 252 health-related publications available in the
ISI database
(1992-2001), only 117 449 (3.57%) were related
to mental health. There was
very low variability in the proportion
of mental health to health-related
publications across the
10-year period (2.95%-3.86%).
All high-income countries (see World Bank
(2003) criteria), with 15% of
the world's population, contributed 94%; low- and middle-income countries,
with more than 85% of the world's population, contributed 6% to
internationally accessible mental health literature
(Table 1). The USA and UK, with
5.6% of the world's population, contributed more than 50%; 14 leading
high-income countries (with more than 1% contribution for the majority of
years under consideration), including the USA and UK, with 12.9% of the
world's population (<7% of all countries) contributed 90% (see
data supplement to the online
version of this paper). Fifty-one countries (more than a quarter) among those
listed as member states of the World Health Organization (WHO) were virtually
unrepresented (<0.001% of internationally accessible mental health
publications in any year) in the database (data not shown). Some of the
unrepresented countries are mid-sized countries with populations above 5
million (e.g. Chad, Guinea, Haiti, Honduras, Lao People's Democratic Republic,
Rwanda and Somalia). The contribution from the USA decreased from 49% to 43%
over the 10-year time period.
View this table:
[in this window]
[in a new window]
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Table 1 Percentage of world production of mental health publications (total
n=117449) according to World Bank income groups
|
View this table:
[in this window]
[in a new window]
|
Data supplement 1 Percentage of world production of mental health publications (total
n=117449): breakdown of contributions by countries contributing more
than 1% of the literature
|

DISCUSSION
Mental health research publications form a much smaller fraction
of health
research publications in comparison with the relative
burden of mental illness
(
Rochon et al, 2004;
present study).
Currently priorities for health research are established by
a
combination of explicit and implicit means. Priorities may
be affected by the
personal scientific interests of researchers,
the priorities of those who
serve as reviewers for grants and
the philanthropic interests of those who
privately fund research,
the availability of researchers or institutions that
specialise
in a subject area, government policy, stakeholder lobbying and
media interest, and the profit potential of the research
(
Jorm et al, 2002).
Mental health research has obviously received
low priority, as exemplified by
the fact that the National
Health and Medical Research Council (NHMRC) of
Australia spent
only 8.9% of its funds on mental health research compared with
the 19.1% contribution of mental disorders to disease burden
in Australia
(
Jorm et al, 2002).
Similarly, the scientific
interests of editors, reviewers, researchers and
readers (subscribers),
and overall context of publishing could also play a
role in
the underrepresentation of mental health publications in general
health journals. A widespread acceptance of mental health as
an issue
deserving attention, a perception that mental health
research can be
scientific and advocacy for mental health research
are needed to improve the
current situation. Some noteworthy
efforts have been made in this direction.
The World Health Report 2001
(
WHO, 2001) and a report of
the Surgeon General
(
US Department of
Health & Human Services, 1999) have called
for greater support
for mental health research.
It is evident that the 10/90 divide in health research output
(Canadian Medical Association Journal,
2004; Paraje et al,
2005) also holds true for the mental health field. A very limited
amount (6%) of internationally accessible mental health literature emanates
from low- and middle-income countries. The very slight increase observed in
the production of middle-income countries is negated by the decrease in the
already low production of low-income countries.
Earlier studies of a limited number of publications in terms of journals
(<10) and time periods covered (2 years) reported similar findings
(Patel & Sumathipala, 2001;
Parker & Parker, 2002). Limited access to information, lack of advice on research design and
statistics, difficulty in writing in a foreign language, overall material,
financial, policy and infrastructural constraints, and limited appreciation by
editorial offices of the research needs of, and realities in, low- and
middle-income countries may constitute barriers that impede publication of
mental health research from these countries in widely accessible journals
(Bulletin of the World Health Organization,
2004).
The fact that the proportional decrease in the contribution of the USA was
balanced by an increase in mental health publications from other high-income
countries suggests that the 10/90 divide is not going away and that active
efforts are required to improve the mental health research situation in low-
and middle-income countries. The results of this study highlight the need to
improve the research infrastructure and capacity to conduct and disseminate
mental health research in general, and in particular in low- and middle-income
countries. The WHO has called for a substantial increase in investment in
mental health research capacity, particularly in low- and middle-income
countries (WHO, 2003). A joint
statement issued recently by editors of scientific journals publishing mental
health research and the WHO summarised the existing unsatisfactory state
regarding publication of mental health research and offered some steps to
correct these imbalances (Bulletin of the
World Health Organization, 2004). The present study confirms that
the 10/90 divide in mental health research has remained undiminished over 10
years; hence the urgent need to implement the steps suggested by the joint
statement.

ACKNOWLEDGMENTS
We thank Professor Grant Lewison, Department of Information
Science, City
University, London for serving as a scientific
advisor during finalisation of
the search strategy for this
project.

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