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Psychodynamic and Psychotherapeutic Problems in Connection with Imipramine (Tofranil) Intake

Published online by Cambridge University Press:  08 February 2018

H. Azima
H. Azima*
Affiliation:
McGill University and Allen Memorial Institute, Montreal
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Extract

Since the preliminary studies in imipramine (Tofranil) (1, 2, 3, 4) demonstrated the potent anti-depressant activity of this substance, attempts have been made to pin-point the differential effects of the drug on psychodynamic structure. These were reported in two previous studies (5, 6). The purpose of the present communication is to elaborate on the information gained in the latter experiments, and their consequent application to the psychotherapy of depressions and other mental syndromes.

Type
Original Articles
Information
Journal of Mental Science , Volume 107 , Issue 446 , January 1961 , pp. 74 - 82
Copyright
Copyright © Royal College of Psychiatrists, 1961 

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References

1. Kuhn, R., “The treatment of depressive states with an Iminodibenzyl derivative (G-22355)”, Schweiz, med. Wchnschr., 1957, 87, 1135–1140.Google Scholar
2. Azima, H., & Vispo, R., “Imipramine, a potent new anti-depressant compound”, Am. J. Psychiat., 1958, 115, 245–246.CrossRefGoogle Scholar
3. Lehmann, H., Cahn, C. H., & de Verteuil, R. L., “The Treatment of Depressive Conditions with G-22355”. Canad. Psychiat. A. J., 1958, 3, 155.Google Scholar
4. Azima, H., “Imipramine (Tofranil). A new Drug for the Depressed”, Canad. Med. Ass. J., 1959, 80, 535–540.Google Scholar
5. Azima, H., & Vispo, R., “Effects of Imipramine (Tofranil) on Depressive States”, A.M.A. Arch. Neurol. & Psychiat., 1959, 81, 658–664.Google Scholar
6. Azima, H., “Some methodological points in psychodynamic studies during pharmacotherapy”, Biopsyche (in press).Google Scholar
7. Azima, H., Azima, Fern J., & Durost, H., “Alteration of schizophrenic dynamic structure concomitant with Reserpine administration”, in Biological Psychiatry, 1959, pp. 244–258. Grune & Stratton Inc. Google Scholar
8. Klein, , Melanie, , “A contribution to the psychogenesis of manic-depressive states”, in Contribution to Psychoanalysis, 1950, pp. 282–311. London: Hogarth Press.Google Scholar
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