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Phenothiazines in Urine

Published online by Cambridge University Press:  08 February 2018

S. Gold ,
P. D. Griffiths  and
R. G. Huntsman
P. D. Griffiths
Affiliation:
Guy's Hospital, S.E.1
R. G. Huntsman
Affiliation:
Peterborough Group of Hospitals
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Extract

Patients in the care of the Department of Psychological Medicine, Guy's Hospital, who are receiving moderate and large doses of phenothiazine drugs are regularly tested for evidence of hepatic or haematological disturbance. In the course of such an investigation, when the urine of a schizophrenic patient was tested with modified Ehrlich's reagent for urobilinogen, it was remarked that a deep blue colour was produced. The patient had been receiving 600 mg. of chloropromazine daily in divided doses for the previous 10 days, and as no other cause for this unusual result could be found, the phenothiazine was considered to be responsible.

Type
Original Articles
Information
Journal of Mental Science , Volume 108 , Issue 452 , January 1962 , pp. 88 - 94
Copyright
Copyright © Royal College of Psychiatrists, 1962 

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