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Serum Uric Acid and Cholesterol Levels in Mongoloid and Non-Mongoloid Oligophrenics

Published online by Cambridge University Press:  29 January 2018

L. M. Dalderup
Affiliation:
The Netherlands Institute of Nutrition, Wageningen
H. Affourtit-Leeuw
Affiliation:
The Netherlands Institute of Nutrition, Wageningen
P. A. F. van der Spek
Affiliation:
Psychiatric Hospital St. Bavo, Noordwijkerhout
G. H. M. Keller
Affiliation:
The Netherlands Institute of Nutrition, Wageningen
H. J. Duin
Affiliation:
Unilever Research Laboratory, Vlaardingen
H. de Iongh
Affiliation:
Unilever Research Laboratory, Vlaardingen

Extract

A number of observations have been published with regard to elevated serum uric acid levels in patients with atherosclerotic (Eidlitz, 1961, 1962) and coronary disease (Gertler, Garn and Levine, 1951) and hyperuricaemia after myocardial infarction (Dreyfuss, 1959; Kohn and Prozan, 1959). Work has also been done on dominant traits for hyperuricaemia together with hypercholesterolaemia (Adlersberg, 1949; Harris-Jones, 1957; Salvini and Verdi, 1959; Schoenfeld and Goldberger, 1963). A greater incidence of cardiovascular diseases among gouty patients than among others has been noted (Gertler and Oppenheimer, 1953), as well as a tendency for spontaneous changes in the serum cholesterol level to be associated with changes of similar direction and magnitude in the serum uric acid level (Schoenfeld and Goldberger, 1963). In view of all these observations, an investigation was undertaken to ascertain whether the serum uric acid levels change with dietary fat composition as do the serum cholesterol levels.

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1966 

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