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Cerebral Biopsy in the Investigation of Presenile Dementia

II. Pathological Aspects

Published online by Cambridge University Press:  29 January 2018

W. Thomas Smith ,
Eric Turner  and
Myre Sim
W. Thomas Smith
Affiliation:
University of Birmingham: Department of Pathology, Medical School, Birmingham, 15
Myre Sim
Affiliation:
Queen Elizabeth Hospital, Birmingham, 15
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Extract

This investigation is concerned with the histological changes found in cerebral biopsy specimens taken from 59 patients with presenile dementia. We have defined the presenile dementias as organic dementing diseases occurring before the age of 65; although 5 of the patients were a few years older than this at the time of biopsy, in all cases there was unequivocal evidence that the dementia was established before the 65th year. The clinical findings in 56 of these patients are described in the preceding paper (Sim, Turner and Smith, 1966).

Type
Research Article
Information
The British Journal of Psychiatry , Volume 112 , Issue 483 , February 1966 , pp. 127 - 133
Copyright
Copyright © Royal College of Psychiatrists, 1966 

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References

Corsellis, J. A. N., and Brierley, J. B. (1954). “An unusual type of presenile dementia (atypical Alzheimer's disease with amyloid vascular change.” Brain, 77, 571–87.Google Scholar
Diezel, P. B. (1957). “Histochemical study of the primary lipidoses.” In Cerebral Lipidoses (ed. Cumings, J. N., and Lowenthal, A.). Oxford.Google Scholar
Divry, P. (1927). “Etude histo-chimique des plaques séniles.” J. Beige Neurol. Psych., 27, 643–57.Google Scholar
Dixon, K. C. (1953). “A periodic acid-silver method for neurones.” J. Path. Bact., 66, 539–44.CrossRefGoogle ScholarPubMed
Friede, R. L., and Magee, K. R. (1962). “Alzheimer's disease. Presentation of a case with enzymatichistochemical observations.” Neurology, 12, 213–22.Google Scholar
Green, M. A., Stevenson, L. D., Fonseca, J. E., and Wortis, S. B. (1952). “Cerebral biopsy in patients with presenile dementia.” Dis. nerv. Syst., 12, 3–7.Google Scholar
Hirano, A. and Zimmerman, H. M. (1962). “Silver impregnation of nerve cells and fibres in celloidin sections.” Arch. Neurol. (Chicago), 6, 114–22.CrossRefGoogle ScholarPubMed
van der Horst, L., Stam, F. C., and Wigboldus, J. M. (1960). “Amyloidosis and senile and pre-senile involutional processes of the central nervous system.” J. nerv. ment. Dis., 13, 578–87.Google Scholar
Jones, D. B. (1957). “Nephrotic glomerulonephritis.” Amer. J. Path., 33, 313–29.Google Scholar
Kidd, M. (1964). “Alzheimer's disease. An electron-microscopical study.” Brain, 87, 307–20.Google Scholar
Lampert, P., Tom, M. I., and Cumings, J. N. (1962). “Encephalopathy in Whipple's disease.” Neurology, 12, 65–71.CrossRefGoogle ScholarPubMed
McMenemey, W. H. (1940). “Alzheimer's disease. A report of six cases.” J. Neurol. Neurosurg. Psychiat., 3, 211–40.CrossRefGoogle ScholarPubMed
McMenemey, W. H. (1963a). “The dementias and progressive diseases of the basal ganglia”. In: Greenfield's Neuropathology. London.Google Scholar
McMenemey, W. H. (1963b). “Alzheimer's disease: problems concerning its concept and nature.” Acta neurol. Scand., 39, 369–80.CrossRefGoogle Scholar
Madow, L., and Alpers, B. J. (1951). “Encephalitic form of metastatic carcinoma.” Arch. Neurol. Psychiat. (Chicago), 65, 161–73.CrossRefGoogle ScholarPubMed
Margolis, , George, (1953). “Observations on senile cerebral deposits using the periodic acid—Scruff's technic.” Amer. J. Path., 29, 588.Google Scholar
Margolis, , George, (1959). “Senile cerebral disease.” Lab. Invest., 8, 335–70.Google Scholar
Matthews, W. B. (1965). “Sarcoidosis of the nervous system.” J. Neurol. Neurosurg. Psychiat., 28, 23–29.CrossRefGoogle ScholarPubMed
Meyer, A., and Meyer, , Margaret, (1949). “Nucleoprotein in the nerve cells of mental patients. A critical remark.” J. ment. Sci., 95, 180–1.Google Scholar
Nevin, S., McMenemey, W. H., Behrman, S., and Jones, D. P. (1960). “Subacute spongiform encephalopathy —a subacute form of encephalopathy attributable to vascular dysfunction (spongiform cerebral atrophy).” Brain, 83, 519–64.Google Scholar
Olszewski, J. (1962). “Subcortical arteriosclerotic encephalopathy.” World Neurol., 3, 359–75.Google ScholarPubMed
Silverstein, A., Fener, M. M., and Silzbach, L. E. (1965). “Neurologic sarcoidosis.” Arch. Neurol. (Chicago), 12, 1–11.CrossRefGoogle ScholarPubMed
Sim, M., and Smith, W. T. (1955). “Alzheimer's disease confirmed by cerebral biopsy: a therapeutic trial with cortisone and A.C.T.H.” J. ment. Sci., 101, 604–9.CrossRefGoogle ScholarPubMed
Sim, M., and Sussman, I. (1962). “Alzheimer's disease: its natural history and differential diagnosis.” J. nerv. ment. Dis., 135, 489–99.Google Scholar
Sim, M., Turner, E., and Smith, W. T. (1966). “Cerebral biopsy in the investigation of presenile dementia. I. Clinical aspects.” Brit. J. Psychiat., 112, 119–125.Google Scholar
Smith, W. T., French, J. M., Gottsman, M., Smith, A. J., and Wakes-Miller, J. A. (1965). “Cerebral complications of Whipple's disease.” Brain, 88, 137–50.Google Scholar
Spatz, H. (1952). “La maladie de Pick, les atrophies systematisées progressives et la sénescence cérébrale prématurée localisée.” Proc. 1st. Int. Cong. Neuropath. (Rome), Turin, 2, 375–406.Google Scholar
Terry, R. D., Gonatas, N. K., and Weiss, M. (1964). “Ultrastructural studies in Alzheimer's presenile dementia.” Amer. J. Path., 44, 269–97.Google ScholarPubMed
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