Hostname: page-component-7c8c6479df-94d59 Total loading time: 0 Render date: 2024-03-28T17:47:49.877Z Has data issue: false hasContentIssue false

Persistent Oral Dyskinesia in Female Mental Hospital Patients

Published online by Cambridge University Press:  29 January 2018

I. G. Pryce
Affiliation:
Whitchurch Hospital, Cardiff
H. Edwards
Affiliation:
Whitchurch Hospital, Cardiff

Extract

An association between certain persistent oral dyskinesias and medication with phenothiazines has been observed in middle-aged and elderly women for several years. In most of the published reports it is held that the phenothiazines are an important cause of the abnormal movements, since phenothiazines are known to exert a selective action on the basal ganglia. Other possible causes, however, are almost invariably present. These are brain damage from disease, leucotomy or electroconvulsive therapy (Hunter, Earl and Janz, 1964; Hunter, Earl and Thornicroft, 1964; Uhrbrand and Faurbye, 1960), and buccal factors such as ill-fitting dentures or the edentulous state (Joyston-Bechal, 1965; Evans, 1965). Similar dyskinesias are also said to occur with brain damage when phenothiazines have not been given (Rosin and Exton-Smith, 1965).

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1966 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Evans, J. H. (1965). “Persistent oral dyskinesia in treatment with phenothiazine derivatives.” Lancet, i, 458460.Google Scholar
Faurbye, A., Rasch, P.-J., Petersen, P. B., Brandborg, G., and Pakkenberg, H. (1964). “Neurological symptoms in pharmacotherapy of psychoses.”, Acta psychiat. Scand., 40, 1027.Google Scholar
Hunter, R., Earl, C. J., and Janz, D. (1964). “A syndrome of abnormal movements and dementia in leucotomized patients treated with phenothiazines.” J. Neurol. Neurosurg. Psychiat., 27, 219223.Google Scholar
Hunter, R., Earl, G. J., and Thornicroft, S. (1964). “An apparently irreversible syndrome of abnormal movements following phenothiazine medication.” Proc. Roy. Soc. Med., 57, 758762.Google Scholar
Joyston-Bechal, M. P. (1965). “Persistent oral dyskinesia in treatment with phenothiazine derivatives.” Lancet, i, 600601.Google Scholar
Rosin, A. J., and Exton-Smith, A. N. (1965). “Persistent oral dyskinesia in treatment with phenothiazine derivatives.” Lancet, i, 651.Google Scholar
Shapiro, M. B., Post, F., Lofving, B., and Inglis, J. (1956). “Memory function in psychiatric patients over sixty, some methodological and diagnostic implications.” J. ment. Sci., 102, 233246.Google Scholar
Uhrbrand, L., and Faurbye, A. (1960). “Reversible and irreversible dyskinesia after treatment with perphenazine, chlorpromazine, reserpine and electroconvulsive therapy.” Psychopharmacologia, 1, 408418.Google Scholar
Walton, D., White, J. G., and Black, D. A. (1959). “A modified word-learning test: a cross-validation study.” Brit. J. med. Psychol., 32, 213220.CrossRefGoogle Scholar
Submit a response

eLetters

No eLetters have been published for this article.