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Amitriptyline and Perphenazine in Depressive Illness a Controlled Trial

Published online by Cambridge University Press:  29 January 2018

Ijaz Haider
Ijaz Haider*
Affiliation:
St. Francis and Hurstwood Park Hospitals, Haywards Heath, Sussex; Severalls Hospital, Colchester, Essex
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Extract

This paper describes a “double-blind” trial comparing ‘Triptafen’ tablets—each containing amitriptyline hydrochloride 25 mg. and perphenazine 2 mg.—with a matching placebo in the treatment of depressive illness.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 113 , Issue 495 , February 1967 , pp. 195 - 199
Copyright
Copyright © Royal College of Psychiatrists, 1967 

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References

Medical Research Council (1965). “Clinical trial of the treatment of depressive illness.” Report by the Clinical Psychiatry Committee. Brit. med. J., i, 881–886.Google Scholar
Ernst, E. M. (1963). “Treatment of anxiety and depression in general practice.” Penn. med. J., 66, 43–45.Google Scholar
Martins, J. K. (1966). “Combined amitriptyline-perphenazine (Etrafon) compared with chlordiazepoxide hydrochloride: a double-blind, crossover study.” Curr. Therap. Res., 8, 17–22.Google Scholar
Mattey, W. E. (1963). “Combination therapy for relief of anxiety and depression.” Ibid., 5, 310–318.Google Scholar
Smith, M. E. (1963). “Perphenazine and amitriptyline as adjuncts to psychotherapy.” Amer. J. Psychiat., 120, 76–77.Google Scholar
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