Hostname: page-component-7c8c6479df-xxrs7 Total loading time: 0 Render date: 2024-03-28T11:14:56.668Z Has data issue: false hasContentIssue false

Plasma II-Hydroxycorticosteroids in Affective Disorders

Published online by Cambridge University Press:  29 January 2018

B. W. L. Brooksbank
Affiliation:
Medical Research Council Neuropsychiatric Research Unit, Carshalton, and Greenbank, West Park Hospital, Epsom, Surrey
Alec Coppen
Affiliation:
Medical Research Council Neuropsychiatric Research Unit, Carshalton, and Greenbank, West Park Hospital, Epsom, Surrey

Extract

From diverse physiological and psychological studies in animals and in man, it is generally concluded that increased secretion of adrenocortical steroids accompanies emotional stress. The relationship between mood, especially the pathological changes of mood found in a depressive illness, and adrenocortical hormones is not so clearly defined.

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1967 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Anderson, W. McC., and Dawson, J. (1965). “The variability of plasma 17-OHCS levels in affective illness and schizophrenia.” J. psychosom. Res., 9, 237.CrossRefGoogle Scholar
Beck, A. T., Ward, C. H., Mendelson, M., Mock, J., and Erbaugh, J. (1961). “An inventory for measuring depression.” Arch. gen. Psychiat., 4, 561.CrossRefGoogle ScholarPubMed
Brambilla, F., and Nuremberg, T. (1963). “Adrenal cortex function of cyclothymic patients in depressive phase.” Dis. nerv. Syst., 24, 727.Google Scholar
Braunsberg, H., and James, V. H. T. (1960). “The fluorometric determination of adrenocortical steroids.” Anal. Biochem., 1, 452.CrossRefGoogle Scholar
Bunney, W. E., Hartmann, E. L., and Mason, J. W. (1965). “Study of a patient with 48-hour manic-depressive cycles.” Arch. gen. Psychiat., 12, 619.CrossRefGoogle ScholarPubMed
Bunney, W. E., Hartmann, E. L., Mason, J. W., and Hamburg, D. A. (1965). “Correlations between behavioural variables and urinary 17-hydroxycorticosteroids in depressed patients.” Psychosom. Med., 27, 299.CrossRefGoogle ScholarPubMed
Bunney, W. E., Hartmann, E. L., Roatch, J. F., and Hamburg, D. A. (1965). “A psychoendocrine study of severe psychotic depressive crises.” Amer. J. Psychiat., 122, 72.CrossRefGoogle Scholar
Cope, C. L. (1965). Adrenal Steroids and Disease. London.Google Scholar
Coppen, A. (1966). “The Marke-Nyman temperament scale: an English translation.” Brit. J. med. Psychol. 39, 55.CrossRefGoogle ScholarPubMed
Coppen, A. Fry, D. E., Julian, T., and Marks, V. (1966). To be published.Google Scholar
Coppen, A. Fry, D. E., Julian, T., and Shaw, D. M. (1963). “Mineral metabolism in melancholia.” Brit. med. J., ii, 1439.CrossRefGoogle Scholar
Coppen, A. Fry, D. E., Julian, T., and Shaw, D. M. Malleson, A., and Costain, R. (1966). “Mineral metabolism in mania.” Ibid., i, 71.Google Scholar
Ekman, H., Håkansson, B., McCarthy, J. D., Lehman, J., and Sjögren, B. (1961). “Plasma 17-hydroxycorticosteroids in Cushing's syndrome.” J. clin. Endocrin. Metab., 21, 684.CrossRefGoogle ScholarPubMed
Eysenck, H. J. (1959). Manual of the Maudsley Personality Inventory. London.Google Scholar
Ferguson, H. C., Bartram, A. C. G., Fowlie, H. C., Cathro, D. M., Birchall, K., and Mitchell, F. L. (1964). “A preliminary investigation of steroid excretion in depressed patients before and after electro-convulsive therapy.” Acta endocrin., 47, 58.Google Scholar
Gibbons, J. L. (1964). “Cortisol secretion rate in depressive illness.” Arch. gen. Psychiat., 10, 572.CrossRefGoogle ScholarPubMed
Gibbons, J. L. (1965). “Endocrine changes in depressive illness.” Proc. roy. Soc. Med., 58, 519.CrossRefGoogle Scholar
Gibbons, J. L. (1966). “Studies on the mechanism of increased adrenocortical activity in emotional distress.” 2nd Int. Congr. Hormonal Steroids, Milan; Excerpta Medico. International Congress Series No. 111, Abstr. No. 370.Google Scholar
Gibbons, J. L. and McHugh, P. R. (1962). “Plasma Cortisol in depressive illness.” J. psychiat. Res., 1, 162.CrossRefGoogle ScholarPubMed
Jakobson, T., Stenbäck, A., Strandström, L., and Rimón, R. (1966). “The excretion of urinary 11-deoxy- and 11-oxy-17-hydroxy-corticosteroids in depressive patients during basal conditions and during the administration of methopyrapone.” J. psychosom. Res., 9, 363.CrossRefGoogle ScholarPubMed
Kurland, H. D. (1964). “Steroid excretion in depressive disorders.” Arch. gen. Psychiat., 10, 554.CrossRefGoogle ScholarPubMed
Lingjaerde, P. S. (1964). “Plasma hydrocortisone in mental diseases.” Brit. J. Psychiat., 110, 423.CrossRefGoogle ScholarPubMed
Mattingly, D. (1962). “A simple fluorimetric method for the estimation of free 11-hydroxycorticoids in human plasma.” J. clin. Path., 15, 374.CrossRefGoogle ScholarPubMed
Mendels, J. (1965). “Electroconvulsive therapy and depression: II. significance of endogenous and reactive syndromes.” Brit. J. Psychiat., 111, 682.CrossRefGoogle Scholar
Metcalfe, M., and Goldman, E. (1965). “Validation of an inventory for measuring depression.” Ibid., 111, 240.Google ScholarPubMed
Michael, R. P., and Gibbons, J. L. (1963). “Interrelationships between the endocrine system and neuropsychiatry.” Intern. Rev. Neurobiol., 5, 243.CrossRefGoogle Scholar
Quarton, G. C., Clark, L. D., Cobb, S., and Bauer, W. (1955). “Mental disturbances associated with ACTH and cortisone: a review of explanatory hypotheses. Medicine, 34, 13.CrossRefGoogle ScholarPubMed
Rome, H. P., and Braceland, F. J. (1952). “The psychological response to ACTH, cortisone, hydrocortisone, and related steroid substances.” Amer. J. Psychiat., 108, 641.CrossRefGoogle ScholarPubMed
Schwartz, M., Mandell, A. J., Green, R., and Ferman, R. (1966). “Mood, motility and 17-hydroxycorticoid excretion; a polyvariable case study.” Brit. J. Psychiat., 112, 149.CrossRefGoogle ScholarPubMed
Shaw, D. M., and Coppen, A. (1966). “Potassium and water distribution in depression.” Ibid., 112, 269.Google ScholarPubMed
Stenbäck, A., Jakobson, T., and Rimón, R. (1966). “Depression and anxiety ratings in relation to the excretion of urinary total 17-hydroxycorticosteroids in depressive subjects.” J. psychosom. Res., 9, 355.CrossRefGoogle Scholar
Van Der Vies, J. (1961). “Individual determination of Cortisol and corticosterone in a single small sample of peripheral blood.” Acta endocrin., 38, 399.Google Scholar
Vermeulen, A., and Van Der Straeten, M. (1964). “Determination of plasma Cortisol by a fluorimetric method.” J. clin. Endocrin. Metab., 24, 1188.CrossRefGoogle Scholar
Wasserman, M. J., Belton, N. R., and Millichap, J. G. (1965). “Effect of corticotrophin (ACTH) on experimental seizures.” Neurology, 15, 1136.CrossRefGoogle ScholarPubMed
Yates, F. E., and Urquhart, J. (1962). “Control of plasma concentrations of adrenocortical hormones.” Physiol. Rev., 42, 359.CrossRefGoogle ScholarPubMed
Submit a response

eLetters

No eLetters have been published for this article.