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A Double-Blind Trial of Amitriptyline/Perphenazine, Perphenazine and Placebo in Chronic Withdrawn Inert Schizophrenics

Published online by Cambridge University Press:  29 January 2018

A. D. Collins  and
J. Dundas
A. D. Collins
Affiliation:
High Royds Hospital, Menston, Yorkshire
J. Dundas
Affiliation:
High Royds Hospital, Menston, Yorkshire
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Extract

Since the introduction of chlorpromazine in the early 1950's, various phenothiazine tranquillizers have become established as standard treatment in schizophrenia. However, it is recognized that these drugs have their limitations; every mental hospital contains a large group of schizophrenics whose illness is unaffected or only partially modified by phenothiazines, and some patients develop side-effects sufficiently severe to preclude these drugs being given in fully effective doses.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 113 , Issue 505 , December 1967 , pp. 1425 - 1429
Copyright
Copyright © Royal College of Psychiatrists, 1967 

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References

Ayd, F. J. (1957). “The treatment of ambulatory and hospitalized psychiatric patients with Trilafon.” Dis. nerv. Syst., 18, 394–397.Google Scholar
Ayd, F. J. (1960). “Amitriptyline (Flavil) therapy for depressive reactions.” Psychosomatics, 1, 320–325.CrossRefGoogle Scholar
Calwell, W. P. K., Jacobson, M., and Skarbek, A. (1964). “A comparative study of oxypertine and trifluoperazine in chronic schizophrenia—a new application of the Wing rating scale.” Brit. J. Psychiat., 110, 520–530.CrossRefGoogle Scholar
Dorfmann, W. (1960). “Clinical experiences with amitriptyline (Flavil).” Psychosomatics, 1, 153–155.Google Scholar
Hanlon, T. E., Nussbaum, K., Wittig, B., Hanlon, D. D., and Kurland, A. A. (1964). “The comparative effectiveness of amitriptyline, perphenazine, and their combination in the treatment of chronic psychotic female patients.” J. new Drugs, 4, 52–60.Google Scholar
Karacan, I., Jones, F., and Ersevim, I. (1963). “Evaluation of combined antidepressant and tranquillizing drug (amitriptyline/perphenazine) in the treatment of hospitalized chronic schizophrenic patients.” Amer. J. Psychiat., 120, 500–501.CrossRefGoogle Scholar
Kennedy, R. E., and Miller, J. J. (1963). “Amitriptyline/perphenazine in the treatment of schizophrenia.” Amer. J. Psychiat., 120, 500–501.Google Scholar
Roughead, P., Paterson, L., Barrett, J., Robertson, A., and Whittaker, C. (1960). “Clinical observations on the use of perphenazine (Fentazin) in mental hospital patients.” J. ment. Sci., 106, 571–580.CrossRefGoogle Scholar
Wing, J. K. (1961). “A simple and reliable subclassification of chronic schizophrenia.” Ibid., 107, 862–875.Google Scholar
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