Hostname: page-component-8448b6f56d-xtgtn Total loading time: 0 Render date: 2024-04-16T15:23:40.590Z Has data issue: false hasContentIssue false
  • English
  • Français

The Effect of an Altered Time Regime on Biological Rhythms in a 48-hour Periodic Psychosis

Published online by Cambridge University Press:  29 January 2018

F. A. Jenner ,
J. C. Goodwin ,
M. Sheridan ,
Ilse J. Tauber  and
Mary C. Lobban
F. A. Jenner
Affiliation:
Medical Research Council Unit for Research on the Chemical Pathology of Mental Disorders, Hollymoor Clinic, Hollymoor Hospital, Northfield, Birmingham, 31
J. C. Goodwin
Affiliation:
Medical Research Council Unit for Research on the Chemical Pathology of Mental Disorders, Hollymoor Clinic, Hollymoor Hospital, Northfield, Birmingham, 31
M. Sheridan
Affiliation:
Medical Research Council Unit for Research on the Chemical Pathology of Mental Disorders, Hollymoor Clinic, Hollymoor Hospital, Northfield, Birmingham, 31
Ilse J. Tauber
Affiliation:
Medical Research Council Unit for Research on the Chemical Pathology of Mental Disorders, Hollymoor Clinic, Hollymoor Hospital, Northfield, Birmingham, 31
Mary C. Lobban
Affiliation:
Division of Human Physiology, National Institute for Medical Research, Hampstead, London, N.W.3
Get access Rights & Permissions [Opens in a new window]

Extract

Jenner, Gjessing, Cox, Davies-Jones, Hullin, and Hanna (1967) have presented some biochemical and clinical studies of a patient who showed a remarkably precisely timed manic-depressive psychosis. For the last eleven years the patient has been alternately depressed and lethargic for 24 hours, then elated for 24 hours, and so on almost without fail. Harding, Jeavons, Jenner, Drummond, Sheridan and Howells (1966) published electroencephalographic studies showing the 48-hour rhythm in the patient's electroencephalogram. The harmonic mean, the mean abundance and variability of the alpha rhythm all showed a striking 48-hour cycle. A number of similar patients have been described and are conveniently listed by Menninger-Lerchenthal (1960), Richter (1960), and Bunney and Hartmann (1965). Jenner (1965) made some suggestions about possibly heuristically helpful electronic analogues which might appropriately represent some of the underlying mechanisms of the 48-hour syndromes.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 114 , Issue 507 , February 1968 , pp. 215 - 224
Copyright
Copyright © Royal College of Psychiatrists, 1968 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Aschoff, J. (ed.) (1965). Circadian Clocks. Amsterdam: North Holland Publishing Co.Google Scholar
Aschoff, J. and Wever, R. (1962). “Spontanperiodik des Menschen bei Ausschluss aller Zeitgeber” Naturwissenschaften, 15, 337–342.Google Scholar
Boyce, K., Hanna, S. M., and Jenner, F. A. (1967). In preparation.Google Scholar
Briscoe, A. M., and Ragan, C. (1966). “Diurnal variations in calcium and magnesium excretion in man” Metabolism, 15, 1002–1010.Google Scholar
Brown, F. A. (1965). “A unified theory for biological rhythms.” in Circadian Clocks. Ed. Aschoff, J., pp. 231–261.Google Scholar
Bunney, W. E., Hartmann, E. L. (1965). “Study of a patient with 48 hour manic-depressive cycles. Part i. An analysis of behavioural factors” Arch. gen. Psychiat., 12, 611–618.Google Scholar
Clark, E. P., and Collip, J. B. (1925). “A study of the Tisdall method for the determination of blood serum calcium with a suggested modification” J. biol. Chem., 63, 461–464.CrossRefGoogle Scholar
Halberg, F. (1959). “Physiologic 24-hour periodicity; general and procedural considerations with reference to the adrenal cycle” Z. Vitamin-Hormon-Fermentforsch, 10, 225–296.Google Scholar
Harding, G. F. A., Jeavons, P. M., Jenner, F. A., Drummond, P., Sheridan, M.,† and Howells, G. W. (1966). “The electroencephalogram in three cases of periodic psychosis” Electroenceph. clin. Neurophysiol., 21, 59–66.CrossRefGoogle Scholar
Jenner, F. A. (1963). “Biochemical aspects of disorders of mood” in Neurometabolic Disorders of Childhood. Ed. Holt, K., Livingstone, Edinburgh.Google Scholar
Jenner, F. A. (1965). “A psychotic analogue” in Biomechanics and Related Bio-Engineering Topics. Ed. Kenedi, R. M., Pergamon Press, Oxford. pp. 467–473.Google Scholar
Jenner, F. A., Gjessing, L. R., Cox, J. R., Davies-Jones, A., Hullin, R. P., and Hanna, S. M. (1967). “A manic-depressive psychotic with a persistent forty-eight hour cycle” Brit. J. Psychiat., 113, 895–910.Google Scholar
Lewis, P. R., and Lobban, Mary C. (1956). “Patterns of electrolyte excretion in human subjects during a prolonged period of life on a 22-hour day” J. Physiol., 133, 670–680.Google Scholar
Menninger-Lerchenthal, E. (1960). Periodizität in der Psychopathologie. Maudrich, Vienna.Google Scholar
Mills, J. N. (1966). “Human circadian rhythms” Physiol. Rev., 46, 128–171.Google Scholar
Moroney, M. J. (1951). Facts from Figures. Penguin Books, London.Google Scholar
Norymberski, J. K., Stubbs, R. D., and West, H. F. (1953). “Assessment of adrenocortical activity by assay of 17-ketogenic steroids in urine” Lancet, i, 1276–1281.Google Scholar
Pittendrigh, G. S., and Bruce, V. G. (1959). “Daily rhythms as coupled oscillator systems and their relation to thermo periodism and photo periodism” in Photo-periodism and Related Phenomena in Plants and Animals. Am. Assoc. Advanc. Sci., Washington, D.C., 55, 475–505.Google Scholar
Richter, C. P. (1960). “Biological clocks in medicine and psychiatry: shock-phase hypothesis” Proc. not. Acad. Sci., 46, 1506–1530.CrossRefGoogle Scholar
Schacter, D. (1961). “Fluorometric estimation of magnesium with 8-hydroxy-5-quinoline sulphonate” J. Lab. clin. Med., 58, 495–504.Google Scholar
Smith, S., and Lewty, L. (1959). “Perceptual isolation using a silent room” Lancet, ii, 342–345.CrossRefGoogle Scholar
Sutherland, I. T. (1967). Personal communication. Tromp, S. W. (1963). Medical Biometeorology. Elsevier, London.Google Scholar
Varley, H. (1962). Practical Clinical Biochemistry. 3rd Edition. p. 409. Heinemann, London.Google Scholar
Ward, F., and Shapiro, R. (1961). “Meteorological periodicities” J. Meteorology, 18, 635–656.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.