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A Comparative Trial of Mandrax and Dichloralphenazone

Published online by Cambridge University Press:  29 January 2018

Ijaz Haider
Ijaz Haider*
Affiliation:
Department of Child and Family Psychiatry, Stratheden Hospital, Playfield House, Cupar, Fife, and Severalls Hospital, Colchester, Essex. Present address: Edinburgh University Department of Psychiatry, Royal Edinburgh Hospital, Morningside Park, Edinburgh 10
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Extract

Mandrax is a combination of methaqualone 250 mg. and diphenhydramine 25 mg. Burke and Mahadevan (1966) have found it to be as potent in this dosage as 200 mg. of butobarbitone.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 114 , Issue 509 , April 1968 , pp. 465 - 468
Copyright
Copyright © Royal College of Psychiatrists, 1968 

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References

Boissier, J.-R., Dumont, C., and Malen, C. (1958). “Pharmacological study of a new hypnotic: 2-methyl 3-orthotolyl 4-quinazolone” Therapie, xiii, 30–45.Google Scholar
Burke, H., and Mahadevan, M. (1966). “Preliminary clinical trial of a new hypnotic combination—Mandrax” Clinical Trials Journal, 3, 417–419.Google Scholar
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Parsons, T. W., and Thomson, T. J. (1961). “Methaqualone as a hypnotic” Brit. med. J., i, 171–173.Google Scholar
Weaver, L. C., Jones, W. R., Kerley, T. L. (1963). “Some central nervous system depressant properties of 2-methyl-3-o-tolyl-4 (3H)- quinazolinone (TR 495) (i)” Arch. int. Pharmacodyn., 143, No. 1–2, 119–126.Google Scholar
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