The British Journal of Psychiatry


Glucose tolerance was examined, using intravenous and oral techniques, in fourteen depressed patients before and after recovery. The patients were given 167 g. of glucose daily in addition to their normal diet.

No abnormality in glucose tolerance attributable to depression was observed, and results of both tests showed no significant difference before as compared with after recovery. Fasting plasma non-esterified fatty acids were also measured during the initial glucose tolerance test in 8 patients and were normal.