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The Need for Drug Monitoring in Psychiatric Practice

Published online by Cambridge University Press:  29 January 2018

Quentin Gardiner*
Affiliation:
University Department of Mental Health, Aberdeen

Extract

The national cost of prescriptions for drugs for use in medical practice in the United Kingdome has risen progressively from £35,000,000 in 1949 to well over £100,000,000 a year now (Dunlop, 1965). The number of drugs taken by patients is vast, and the variety of drugs available for prescription is considerable. Prescribed in order to produce a specific therapeutic effect, few drugs, if any, are wholly free from the potential of producing undesirable side-effects. These vary from the trivial to the lethal, from the transient to the permanent. Methods for their accurate detection, qualitative evaluation and risk identification are vital prerequisites to therapeutic safety and refinement. Experimental techniques, using detailed observation on large samples of patients being treated by drugs, have been developed recently. A monitoring system which scans for side-effects of drugs represents a means whereby prospective and cumulative data on the frequency of occurrence and nature of these side-effects can accrue. This is referred to as drug monitoring.

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1968 

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References

Black, A. A. (1966). “Factors predisposing to a placebo response in new out-patients with anxiety states” Brit. J. Psychiat., 112, 557.CrossRefGoogle Scholar
Carstairs, G. M., and Bruhn, J. G. (1962). “Sociological studies of psychiatric out-patient practice” Sociological Review Monograph, 5, 91.Google Scholar
Cluff, L. E., Thornton, G. F., Seidl, L. G., and Smith, J. (1965). “Epidemiological study of adverse drug reactions” Trans. Ass. Amer. Phycns., 78, 255.Google Scholar
Crooks, J., Clark, C. G., Caie, H. B., and Mawson, W. B. (1965). “Prescribing and administration of drugs in hospital” Lancet, i, 373.Google Scholar
Dunlop, D. (1965). “Use and abuse of drugs” Brit. med. J., ii, 437.Google Scholar
Finney, D. J. (1965). “The design and logic of a monitor of drug use” J. chron. Dis., 18, 77.Google Scholar
Kessel, N., and Shepherd, M. (1962). “Neurosis in hospital and general practice” J. ment. Sci., 108, 159.CrossRefGoogle Scholar
Lenz, W., and Knapp, K. (1962). “Die Thalidomid Embryopathie” Dtsch. med. Wschr., 24, 1232.CrossRefGoogle Scholar
Logan, W. P. D., and Cushion, A. A. (1958). Studies on Medical and Population Subjects, No. 14. London: H.M. Stationery Office.Google Scholar
Pollack, B. (1956). “The effect of chlorpromazine on the return rate of 250 patients released from the Rochester State Hospital” Amer. J. Psychiat., 112, 937.CrossRefGoogle Scholar
Pollack, B. (1958). “The effect of chlorpromazine in reducing the relapse rate in 716 released patients: study 3” Ibid., 114, 749.Google Scholar
Renton, C. A., Affleck, J. W., Carstairs, G. M., and Forrest, A. D. (1963). “A follow-up of schizophrenic patients in Edinburgh” Acta psychiat. Scand., 39, 548.Google Scholar
Schimmel, E. M. (1964). “Hazards of hospitalization” Ann. int. Med., 60, 100.CrossRefGoogle ScholarPubMed
Seidl, L. G., Thornton, G. F., and Cluff, L. E. (1965). “Epidemiological studies of adverse drug reactions” Am. J. publ. Hlth., 55, 1170.Google Scholar
Shepherd, M., Fisher, M., Stein, L., and Kessel, W. I. N. (1959). “Psychiatric morbidity in an urban group practice” Proc. roy. Soc. Med., 52, 269.CrossRefGoogle Scholar
Taussig, H. B. (1962). “The thalidomide syndrome” J. Amer. med. Ass., 13, 1106.Google Scholar
Vere, D. W. (1965). “Errors of complex prescribing” Lancet, i, 370.Google Scholar
Wallace, W. F. M. (1965). “Drugs in hospital” Ibid., i, 555.Google Scholar
Willcox, D. R. C., Gillan, R., and Hare, E. H. (1965). “Do psychiatric out-patients take their drugs?” Brit. med. J., ii, 790.CrossRefGoogle Scholar
Wilson, G. M. (1966). “Ill-health due to drugs” Ibid., i, 1065.Google Scholar
Witts, L. J. (1965). “Adverse reactions to drugs” Ibid., ii, 1081.Google Scholar
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