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Adrenocortical Responsiveness during Courses of Electro-convulsive Therapy

Published online by Cambridge University Press:  29 January 2018

A. Elithorn
Affiliation:
Department of Psychological Medicine, Royal Free Hospital, London, W.C.1
P. K. Bridges
Affiliation:
Department of Psychological Medicine, Royal Free Hospital, London, W.C.1
J. R. Hodges
Affiliation:
Department of Pharmacology, Royal Free Hospital Medical School
M. T. Jones
Affiliation:
Department of Pharmacology, Royal Free Hospital Medical School

Extract

In a previous paper (Hodges, Jones, Elithorn and Bridges, 1964) we reported on adrenocortical activity in depressed and schizophrenic patients as revealed by plasma cortisol levels before and after electro-convulsive therapy (E.C.T.). Close similarity was found between the two groups except for three depressed patients who appeared to show considerably higher cortisol levels after the treatment than did the remaining subjects. The patients were examined at random different treatments during the whole treatment course and it appeared possible, both that the observed cortisol response to E.C.T. might depend partly on which treatment of the series in a whole course was under examination, and also that the response of the illness to therapy might be a significant factor. It was therefore decided to observe in a number of subjects the response to successive treatments throughout courses of E.C.T.

Type
Biochemical Studies
Copyright
Copyright © Royal College of Psychiatrists, 1969 

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