The British Journal of Psychiatry
Huntington's Chorea in Northamptonshire


The prevalence of Huntington's Chorea in Northamptonshire in 1967-1968 is compared with its prevalence in 1954-1955. Failure to diagnose, tardy diagnosis, misdiagnosis, dispersal, inaccurate family histories, unsuitable record systems, and inadequate help with contraception for affected families combine to perpetuate the illness.

Surveillance of the pedigrees over almost a generation with retrospective data spanning five to eight generations shows the devastation wrought by the illness not only to afflicted members but to their relatives and dependants.