Hostname: page-component-7c8c6479df-995ml Total loading time: 0 Render date: 2024-03-28T10:53:20.804Z Has data issue: false hasContentIssue false

Prophylactic Lithium: A Double-Blind Trial in Recurrent Affective Disorders

Published online by Cambridge University Press:  29 January 2018

P. I. Melia*
Affiliation:
St. Patrick's Hospital, Dublin 8; Trinity College, University of Dublin

Extract

Lithium was first successfully used in the treatment of mania by Cade (1949), and its efficacy in reducing mania was confirmed in double-blind trials by Schou et al. (1954) and Maggs (1963).

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1970 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Angst, J., Dittrich, A., and Grof, P. (1968). Paper read at meeting of Royal Medico-Psychological Association, Plymouth, July, 1968.Google Scholar
Baastrup, P. C., and Schou, M. (1967). ‘Lithium as a prophylactic agent.’ Arch, gen. Psychiat., 16, 162–72.Google Scholar
Cade, J. P. J. (1949). ‘Lithium salts in the treatment of psychotic excitement.’ Med. J. of Australia, 2, 349–52.Google Scholar
Christodoulou, G. N. (1968). ‘The use of lithium in psychiatry.’ Hosp. Med., 1181–4.Google Scholar
Coppen, A. (1967). ‘The biochemistry of affective disorders.’ Brit. J. Psychiat., 113, 1237–64.CrossRefGoogle ScholarPubMed
Gershon, S., and Yuwiler, A. (1960). ‘Lithium ion: a specific psychopharmacological approach to the treatment of mania.’ J. Neuropsychiat., 1, 229–41.Google Scholar
Hartigan, G. P. (1963). ‘The use of lithium salts in affective disorders.’ Brit. J. Psychiat., 109, 810–14.Google Scholar
H.M. Stationery Office (1968). ‘Studies on Medical and Population Subjects, No. 22: A Glossary of Mental Disorders.’ London.Google Scholar
Maggs, R. (1963). ‘Treatment of manic illness with lithium carbonate.’ Brit. J. Psychiat., 109, 5665.Google Scholar
Melia, P. I. (1967). ‘A pilot trial of lithium carbonate in recurrent affective disorders.’ J. Irish med. Ass., 50, 160–70.Google Scholar
Melia, P. I. (1970). ‘Prophylactic lithium in recurrent affective disorders: a four year study’. In preparation.Google Scholar
Schou, M., Juel-Nielsen, N., Strömgren, E., and Voldly, H. (1954). ‘The treatment of manic psychoses by the administration of lithium salts.’ J. Neurol. Neuropath. Psychiat., 17, 250.CrossRefGoogle ScholarPubMed
Schou, M., Juel-Nielsen, N., Strömgren, E., and Voldly, H. (1957). ‘Biology and pharmacology of the lithium ion.’ Pharmac. Reviews, 9, No. 1. 1758.Google Scholar
Schou, M., Juel-Nielsen, N., Strömgren, E., and Voldly, H. (1963). ‘Normothymics.’ Brit. J. Psychiat., 109. 803–9.Google Scholar
Schou, M., Juel-Nielsen, N., Strömgren, E., and Voldly, H. (1968). ‘Lithium in psychiatric therapy and prophylaxis.’ J. psychiat. Res., 6, 6795.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.