Hostname: page-component-8448b6f56d-jr42d Total loading time: 0 Render date: 2024-04-23T07:52:15.680Z Has data issue: false hasContentIssue false

XYY Karyotype in a Pair of Monozygotic Twins: A 17-Year Life-History Study

Published online by Cambridge University Press:  29 January 2018

John D. Rainer
Affiliation:
New York State Psychiatric Institute, and Associate Professor of Clinical Psychiatry and of Human Genetics and Development, Columbia University, New York, 10032
Syed Abdullah
Affiliation:
Rockland State Hospital, and Instructor in Psychiatry, Columbia University, New York, 10032
Lissy F. Jarvik
Affiliation:
New York State Psychiatric Institute, and Associate Professor of Clinical Psychiatry, Columbia University, New York, 10032

Extract

We have recently had the opportunity to investigate clinical and behavioural characteristics of a pair of 17-year-old twin boys who were discovered to have the XYY karyotype (18). Since these twins, known to this department since infancy, had been studied at the age of three, early direct findings as well as retrospective data are available regarding their symptoms and development.

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1972 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Abdullah, S., Jarvik, L. F., Kato, T., Johnston, W. C., and Lanzkron, J. (1969). ‘Extra Y chromosome and its psychiatric implications.’ Archives of General Psychiatry, 21, 499501.Google Scholar
2. Baker, D., Telfer, M. A., Richardson, C. E., and Clark, G. R. (1970). ‘Chromosome errors in men with antisocial behavior.’ Journal of the American Medical Association, 214, 869–78.Google Scholar
3. Carr, A. C., Forer, B. R., Henry, W. E., Hooker, E., Hutt, M. L., and Piotrowski, Z. A. (1960). The Prediction of Overt Behavior Through the Use of Projective Techniques. Springfield, Illinois: Charles C. Thomas.Google Scholar
4. Char, F., and Borgaonkar, D. S. (1971). ‘Electrocardiogram in males with the 47, XYY karytoype.’ Lancet, i, 1242.Google Scholar
5. Court Brown, W. M. (1968). ‘Males with an XYY sex chromosome complement.’ Journal of Medical Genetics, 5, 341–59.Google Scholar
6. Daly, R. F., Chun, R. W. M., Ewanowski, S., and Osborne, R. H. (1969). ‘The XYY condition in childhood: clinical observations.’ Pediatrics, 43, 852–57.Google Scholar
7. Erwin, F. R. (1967). ‘Psychiatric aspects of epilepsy.’ In: Comprehensive Textbook of Psychiatry (eds. Freedman and Kaplan). Baltimore, 809–13.Google Scholar
8. Fattig, W. D. (1970). ‘XYY survey in a Negro population.’ Journal of Heredity, 61, 10.CrossRefGoogle Scholar
9. Forssman, H. (1970). ‘The mental implications of sex chromosome aberrations.’ British Journal of Psychiatry, 117, 353–63.Google Scholar
10. Gustavson, K. H., and Verneholt, J. (1968). ‘The XYY syndrome in a prepubertal boy.’ Hereditas, 60, 264–66.Google Scholar
11. Hope, K., Philip, A. E., and Loughran, J. M. (1967). ‘Psychological characteristics associated with XYY sex-chromosome complement in a state mental hospital.’ British Journal of Psychiatry, 113, 495–98.Google Scholar
12. Money, J. (1970). ‘Hormonal and genetic extremes at puberty.’ In: The Psychopathology of Adolescence (ed. Zubin and Freedman), New York, 138–55.Google Scholar
13. Noel, B., Quack, B., Durand, Y., and Rethore, M. O. (1969). ‘Les Hommes 47, XYY.’ Annales de Génétique, 12, 223–36.Google Scholar
14. Pearson, P. L., Borrow, M., and Vosa, C. G. (1970). ‘Technique for identifying Y chromosomes in human interphase nuclei.’ Nature, 226, 7880.Google Scholar
15. Penrose, L. S. (1967). ‘Finger print pattern and the sex chromosomes.’ Lancet, i, 298300.Google Scholar
16. Price, W. H. (1968). ‘The electrocardiogram in males with extra Y chromosomes.’ Lancet, i, 1106–8.Google Scholar
17. Price, W. H. and Whatmore, P. B. (1967). ‘Behaviour disorders and pattern of crime among XYY males identified at a maximum security hospital.’ British Medical Journal, 1, 533–36.Google Scholar
18. Rainer, J. D., Jarvik, L. F., Abdullah, S., and Kato, T. (1969). ‘XYY karyotype in monozygotic twins.’ Lancet, ii, 60.Google Scholar
19. Rainer, J. D., Mesnikoff, A., Kolb, L. C., and Garr, A. C. (1960). ‘Homosexuality and heterosexuality in identical twins.’ Psychosomatic Medicine, 22, 251–58.Google Scholar
20. Smith, S. M., and Penrose, L. S. (1955). Monozygotic and dizygotic twin diagnosis.’ Annals of Human Genetics, 19, 273–89.Google Scholar
21. Steiness, E., and Nielsen, J. (1970). ‘The electrocardiogram in males with the 47, XYY karyotype.’ Lancet, i, 1402–3.Google Scholar
22. Tsuboi, T., and Nielsen, J. (1969). ‘Dermatoglyphic study of six patients with the XYY syndrome.’ Human Heredity, 19, 299306.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.