Hostname: page-component-7c8c6479df-94d59 Total loading time: 0 Render date: 2024-03-27T18:13:20.822Z Has data issue: false hasContentIssue false

Schizophrenia in Association with Erythropoietic Protoporphyria — Report of a Case

Published online by Cambridge University Press:  29 January 2018

G. N. Gibney
Affiliation:
St. Vincent's Hospital, Fitzroy, Victoria, 3065, Australia
Ivor H. Jones
Affiliation:
Department of Psychiatry, University of Melbourne, Parkville, Victoria, 3052, Australia
John H. Meek
Affiliation:
Department of Pathology, Royal Children's Hospital, Parkville, Victoria, 3052, Australia

Extract

Erythropoietic Protoporphyria (E.P.P.) may be classified along with the other erythropoietic syndromes of porphyria. It is inherited as an autosomal dominant (Taddeini and Watson, 1968). The condition was first clearly delineated by Magnus, Jarrett, Prankerd and Rimington (1961). They recorded a case with the presenting symptom of solar urticaria in whom faecal excretion of coproporphyrin and protoporphyrin was greatly increased while urinary porphyrins were normal. The red cells contained grossly abnormal amounts of protoporphyrin and coproporphyrin, the plasma increased levels of protoporphyrin. The absence of uroporphyrin distinguished this condition from congenital porphyria (Gunther's Disease).

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1972 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Davidson, K., and Bagley, C. R. (1969). In: Current Problems in Neuropsychiatry (ed. Herrington, R. N.). British Journal of Psychiatry Special Publication No. 4.Google Scholar
Findlay, G. H., Scott, F. P., and Cripps, D. J. (1966). ‘Porphyria and lipid proteinosis: a clinical, histological and biochemical comparison of 19 South African cases.’ Brit. J. Dermatol., 78, 6980.CrossRefGoogle Scholar
Magnus, I. A., Jarrett, A., Prankerd, T. A. J., and Rimington, C. (1961). ‘Erythropoietic protoporphyria. A new porphyria syndrome with solar urticaria due to protoporphyrinaemia.’ Lancet, ii, 448–51.Google Scholar
Redeker, A. G., and Bryan, H. G. (1964). ‘Erythropoietic protoporphyria.’ Lancet, i, 1449–50.Google Scholar
Rimington, C., Magnus, I. A., Ryan, E. A., and Cripps, D. J. (1967). ‘Porphyria and photosensitivity.’ Quart. J. Med., 36, 2957.Google Scholar
Roth, N. (1968). ‘Psychiatric syndromes of porphyria.’ Int. J. Neuropsychiat., 4, 3244.Google ScholarPubMed
Taddeini, L., and Watson, C. J. (1968). ‘The clinical porphyrias.’ Semin. Haematol., 5, 335–69.Google ScholarPubMed
Submit a response

eLetters

No eLetters have been published for this article.