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An Unusual Response to Chlorpromazine Therapy

Published online by Cambridge University Press:  29 January 2018

Paul Williams
Paul Williams*
Affiliation:
Whitchurch Hospital, Cardiff CF4 7XB
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Extract

The production of a catatonic-like state in animals by phenothiazines and related compounds (‘experimental catatonia’) is an important laboratory test in the assessment of neuroleptics (Joyce, 1968). This response is, however, uncommon in humans who are receiving therapeutic doses of this type of drug. Such a case is described, and some of the literature concerning this subject is reviewed.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 121 , Issue 563 , October 1972 , pp. 439 - 440
Copyright
Copyright © Royal College of Psychiatrists, 1972 

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References

Joyce, C. R. B., (ed.) (1968). Psychopharmacology. London: Tavistock Publications.Google Scholar
Kinross-Wright, V. (1955). ‘Complications of chlorpromazine treatment.’ Diseases of the Nervous System, 16(4), 114–18.Google ScholarPubMed
Kline, N. S., and Mettler, F. A. (1961). ‘The extrapyramidal system and schizophrenia’, in The Extra-pyramidal System and Neuroleptics (ed. Bordeleau). Montreal.Google Scholar
May, R. H. (1959). ‘Catatonic-like states following phenothiazine therapy.’ American Journal of Psychiatry, 115(12), 1119–20.CrossRefGoogle ScholarPubMed
Slater, E., and Roth, M. (1969). Clinical Psychiatry. London.Google Scholar
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