Hostname: page-component-76fb5796d-22dnz Total loading time: 0 Render date: 2024-04-25T09:20:16.523Z Has data issue: false hasContentIssue false
  • English
  • Français

Whole Blood 5-Hydroxytryptamine during Treatment of Endogenous Depressive Illness

Published online by Cambridge University Press:  29 January 2018

J. J. Gayford ,
A. L. Parker ,
Eileen M. Phillips  and
A. R. Rowsell
J. J. Gayford
Affiliation:
Roffey Park Hospital, Horsham, Sussex
A. L. Parker
Affiliation:
Roffey Park Hospital, Horsham, Sussex
Eileen M. Phillips
Affiliation:
Department of Clinical Pharmacology, St. Bartholomew's Hospital, London, E.C.1
A. R. Rowsell
Affiliation:
Department of Clinical Pharmacology, St. Bartholomew's Hospital, London, E.C.1
Get access Rights & Permissions [Opens in a new window]

Extract

In the course of a study on endogenous depressive illness, whole blood 5-hydroxytryptamine (5HT) has been recorded in sixteen in-patients at Roffey Park Hospital. Thirteen patients received L-tryptophan 1 G t.d.s. and 3 G nocte, of whom two received in addition phenelzine 15 mg. b.d. for 48 hours followed by 30 mg. b.d. thereafter. Three patients received amitriptyline 25 mg. b.d. and 50 mg. nocte for 48 hours followed by 50 mg. b.d. and 75 mg. nocte thereafter. One patient receiving Ltryptophan had essential hypertension and received α-methylDOPA throughout. Observation continued for six weeks.

Type
Abstract
Information
The British Journal of Psychiatry , Volume 122 , Issue 570 , May 1973 , pp. 597 - 598
Copyright
Copyright © Royal College of Psychiatrists, 1973 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Ashcroft, G. W., Crawford, T. B. B., Binns, J. K., and MacDougall, Elizabeth J. (1964). ‘Estimation of 5-hydroxytryptamine in human blood.’ Clin. Chim. Acta, 9, 364–9.CrossRefGoogle ScholarPubMed
Hamilton, M. (1960). ‘A rating scale for depression.’ J. Neurol. Neurosurg. Psychiat., 23, 56.CrossRefGoogle ScholarPubMed
Submit a response

eLetters

No eLetters have been published for this article.