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Controlled Trial of Dipotassium Clorazepate (‘Tranxene’) in Anxiety

Published online by Cambridge University Press:  29 January 2018

Alan J. Cooper*
Affiliation:
Huntingdon Research Centre, Huntingdon
Ralph V. Magnus
Affiliation:
E. Merck Ltd., Wokingham, Berks
Michael Rose
Affiliation:
Rubery Hill Hospital, Birmingham
André Phanjoo
Affiliation:
Roundways Hospital, Devizes
Neville P. Lancaster
Affiliation:
Royal Edinburgh Hospital, Edinburgh
Patricia Pollard
Affiliation:
Barrow Hospital, Bristol
Patrick A. Knowlson
Affiliation:
Boehringer Ingelheim Ltd., Southern Industrial Estate, Bracknell, Berks
*
Reprints from Dr. Alan J. Cooper.

Extract

Dipotassium clorazepate is a new benzodiazepine derivative with pharmacological and clinical properties resembling diazepam. This report concerns a double-blind placebo-controlled crossover comparison of clorazepate and diazepam which was carried out simultaneously at four centres in the United Kingdom.

Type
Abstract
Copyright
Copyright © Royal College of Psychiatrists, 1973 

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Footnotes

A supply of the drugs used in this study was provided by Boehringer Ingelheim Ltd., Bracknell, Berks.

Present address: Medical Director, E. Merck Ltd., Wokingham, Berks

References

Aitken, R. C. B. (1069). Proc. Roy. Soc. Med., 62. 989–93.Google Scholar
Kellner, R., and Sheffield, B. F. (1966). The Symptom Rating Test: Abridged Manual. University of Liverpool.Google Scholar
Kellner, R., and Sheffield, B. F. (1967a)- Brit. J. Psychiat., 113. 525–6.Google Scholar
Kellner, R., Kelly, A. V., and Sheffield, B. F. (1968). Brit. J. Psychiat., 114. 863–9.Google Scholar
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