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The Relationship of Plasma to Erythrocyte Lithium Levels in Patients Taking Lithium Carbonate

Published online by Cambridge University Press:  29 January 2018

C. R. Lee ,
S. E. Hill ,
M. Dimitrakoudi ,
F. A. Jenner  and
R. J. Pollitt
C. R. Lee
Affiliation:
Medical Research Council Unit for Metabolic Studies in Psychiatry, University Department of Psychiatry, Middlewood Hospital, P.O. Box 134, Sheffield, S6 1TP
S. E. Hill
Affiliation:
Medical Research Council Unit for Metabolic Studies in Psychiatry, University Department of Psychiatry, Middlewood Hospital, P.O. Box 134, Sheffield, S6 1TP
M. Dimitrakoudi
Affiliation:
Medical Research Council Unit for Metabolic Studies in Psychiatry, University Department of Psychiatry, Middlewood Hospital, P.O. Box 134, Sheffield, S6 1TP
F. A. Jenner
Affiliation:
Medical Research Council Unit for Metabolic Studies in Psychiatry, University Department of Psychiatry, Middlewood Hospital, P.O. Box 134, Sheffield, S6 1TP
R. J. Pollitt
Affiliation:
Medical Research Council Unit for Metabolic Studies in Psychiatry, University Department of Psychiatry, Middlewood Hospital, P.O. Box 134, Sheffield, S6 1TP
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Summary

Plasma and erythrocyte lithium levels have been determined repeatedly in twelve patients taking lithium carbonate for affective disorders. In any individual the plot of the plasma lithium level against erythrocyte/plasma ratio is linear, but the ratio can either increase or decrease with increasing plasma lithium concentration. Erythrocyte/plasma ratio is an unsound basis for comparing individual responses to lithium.

Type
Papers
Information
The British Journal of Psychiatry , Volume 127 , Issue 6 , December 1975 , pp. 596 - 598
Copyright
Copyright © Royal College of Psychiatrists, 1975 

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References

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