Hostname: page-component-76fb5796d-x4r87 Total loading time: 0 Render date: 2024-04-25T08:46:52.598Z Has data issue: false hasContentIssue false
  • English
  • Français

Serum Creatine Phosphokinase in Acute Psychosis

Published online by Cambridge University Press:  29 January 2018

Som D. Soni
Som D. Soni*
Affiliation:
Prestwich Hospital, Prestwich, Manchester, M25 7BL
Get access Rights & Permissions [Opens in a new window]

Summary

Fifty-four patients suffering from a variety of psychotic states were graded by their degree of psychomotor activity. Serum creatine Phosphokinase (CPK) levels were found to be related to the degree of psychomotor activity, irrespective of the diagnostic category. Retarded and withdrawn patients had normal serum CPK, but on their return to normal psychomotor activity the CPK levels tended to rise transiently. It appears that unphysiological motor activity has a more direct relationship to the rise of serum CPK than motor activity per se.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 128 , Issue 2 , February 1976 , pp. 181 - 183
Copyright
Copyright © Royal College of Psychiatrists, 1976 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Benozon, A., Hippius, H. & Kanig, H. (1966) Some change in the serum using psychotropic drugs. Journal of Nervous and Mental Disease, 143, 369–76.Google Scholar
2. Coffey, J. W., Heath, R. G. & Guschwan, A. F. (1970) Serum creatine kinase, aldolase and copper in acute and chronic schizophrenics. Biological Psychiatry, 2, 331–9.Google ScholarPubMed
3. Dubo, H., Park, D. C., Pennington, R. J. T., Kalbag, R. M. & Walton, J. N. (1967) Serum creatine kinase in cases of stroke, head injury and meningitis. Lancet, ii, 743–8.CrossRefGoogle ScholarPubMed
4. Gosling, R., Kerry, R. J., Orme, J. E. & Owen, G. (1972) Creatine Phosphokinase activity in newly admitted psychiatric patients. British Journal of Psychiatry, 121, 351–5.Google Scholar
5. Griffiths, P. D. (1966) Serum levels of ATP creatine phosphotransferase: the normal range and effect of muscular activity. Clinica Chimica Acta, 13, 413–20.Google Scholar
6. Harding, T. (1974) Serum creatine kinase in acute psychosis. British Journal of Psychiatry, 125, 280–5.Google Scholar
7. Meltzer, H. Y. (1969) Muscle enzyme release in acute psychosis. Archives of General Psychiatry, 21, 102–12.Google Scholar
8. Meltzer, H. Y. & Moline, R. (1970) Enzymatic activity after exercise: study of psychiatric patients and their relatives. Archives of General Psychiatry, 22, 390–7.CrossRefGoogle ScholarPubMed
9. Meltzer, H. Y. & Moline, R. (1970) Muscle abnormalities in acute psychoses. Archives of General Psychiatry, 23, 481–90.CrossRefGoogle ScholarPubMed
10. Rosalki, S. B. (1967) An improved procedure for serum creatine Phosphokinase estimation. Journal of Laboratory and Clinical Medicine, 69, 696–705.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.