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Mortality in Patients with Schizophrenia, Mania, Depression and Surgical Conditions

A Comparison with General Population Mortality

Published online by Cambridge University Press:  29 January 2018

Ming T. Tsuang
Affiliation:
Department of Psychiatry, University of Iowa College of Medicine, Iowa City, Ia. 52242
Robert F. Woolson
Affiliation:
Department of Preventive Medicine and Environmental Health, University of Iowa College of Medicine, Iowa City, Ia. 52242, USA

Summary

Mortality data are presented from a four-decade follow-up study of 200 schizophrenic, 100 manic, 225 depressive patients, and 160 surgical controls (80 appendicectomy; 80 herniorrhaphy). Data for this analysis were available on 648 (95 per cent) members of the study population. Using sex-age standardized mortality ratios (SMR), the mortality experience of the study population was compared with that of the state of Iowa, the geographical area served by the admitting medical facility for the study group. Results are presented for a four-decade period beginning 1935–44, and ending 1965–74. All three psychiatric groups had a significant increase in mortality risk. This was most pronounced in the first decade following admission, although schizophrenic patients, especially females, continued to show a significant excess of deaths throughout the entire four decades of the follow-up period. During no decade of the follow-up period did the mortality of the surgical controls differ significantly from that of the Iowa population.

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists 1977 

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References

1 Alstrom, C. H. (1942) Mortality in mental hospitals. Acta Psychiatrica et Neurologica Scandinavica, Suppl 24.Google Scholar
2 Babigian, H. M. & Odoroff, C. L. (1969) The mortality experiences of a population with psychiatric illness. American Journal of Psychiatry, 126, 470–80.Google Scholar
3 Bratfos, O. & Huag, J. O. (1968) The course of manic-depressive psychosis: a follow-up investigation of 215 patients. Acta Psychiatrica Scandinavica, 44, 89112.Google Scholar
4 Essen-Moller, E. (1935) Untersuchungen über die Fruchtbarkeit gewisser Gruppen von Geisteskranken. Acta Psychiatrica Scandinavica, Suppl 8.Google Scholar
5 Flood, R. A. & Seager, C. P. (1968) A retrospective examination of psychiatric case records of patients who subsequently committed suicide. British Journal of Psychiatry, 114, 443–50.Google Scholar
6 Innes, G. & Millar, W. M. (1970) Mortality among psychiatric patients. Scottish Medical Journal, 15, 143–8.Google Scholar
7 Kendell, R. E. (1975) The concept of disease and its implications for psychiatry. British Journal of Psychiatry, 127, 305–15.CrossRefGoogle ScholarPubMed
8 Larsson, T. & Sjogren, T. (1954) A methodological, psychiatric and statistical study of a large Swedish rural population. Acta Psychiatrica et Neurologica Scandinavica, Suppl 89.Google Scholar
9 Lindelius, R. (1970) A study of schizophrenia: a clinical, prognostic, and family investigation. Acta Psychiatrica Scandinavica, Suppl 216.Google Scholar
10 Malzberg, B. (1953) Rates of discharge and rates of mortality among first admissions to the New York civil state hospitals. Mental Hygiene, 37, 619–54.Google Scholar
11 Morrison, J., Clancy, J., Crowe, R. & Winokur, G. (1972) The Iowa 500: I. Diagnostic validity in mania, depression, and schizophrenia. Archives of General Psychiatry, 27, 457–61.Google Scholar
12 Ødegaard, Ø. (1952) The excess mortality of the insane. Acta Psychiatrica Scandinavica, 27, 353–67.CrossRefGoogle Scholar
13 Pokorny, A. D. (1966) A follow-up study of 618 suicidal patients. American Journal of Psychiatry, 112, 1109–16.Google Scholar
14 Rorsman, B. (1974) Mortality among psychiatric patients. Acta Psychiatrica Scandinavica, 50, 354–75.Google Scholar
15 Roth, M. (1972) Recent progress in the psychiatry of old age and its bearing on certain problems of psychiatry in earlier life. Biological Psychiatry, 5, 103–25.Google ScholarPubMed
16 Sainsbury, P. (1968) Suicide and depression. In Recent Developments in Affective Disorders (eds Coppen, A. and Walk, A.). London.Google Scholar
17 Tsuang, M. T. & Winokur, G. (1975) The Iowa 500: Field work in a 35-year follow-up of depression, mania, and schizophrenia. Canadian Psychiatric Association Journal, 20, 359–65.Google Scholar
18 U.S. Census Bureau (1940) U.S. Census of Population: Population Characteristics, 4(2), 743.Google Scholar
19 U.S. Census Bureau (1950) U.S. Census of Population: Population Characteristics, 2(15), 40–2.Google Scholar
20 U.S. Census Bureau (1960) U.S. Census of Population: Population Characteristics, 1(17), 42–3.Google Scholar
21 U.S. Census Bureau (1970) U.S. Census of Population: Population Characteristics, 1(B17), 64.Google Scholar
22 U.S. Census Bureau (1940) Vital Statistics of the U.S., 1, 186–7.Google Scholar
23 U.S. Dept of Health, Education and Welfare (1950) Vital Statistics of the U.S., 3, 308.Google Scholar
24 U.S. Dept of Health, Education and Welfare (1960) Vital Statistics of the U.S., 2(B), 200.Google Scholar
25 U.S. Dept of Health, Education and Welfare (1970) Vital Statistics of the U.S., 2(B), 258.Google Scholar
26 Winokur, G. & Tsuang, M. T. (1975) The Iowa 500: Suicide in mania, depression, and schizophrenia. American Journal of Psychiatry, 132, 650–1.Google Scholar
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