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Hallucinogenic N-Methylated Indolealkylamines in the Cerebrospinal Fluid of Psychiatric and Control Populations

Published online by Cambridge University Press:  29 January 2018

Lionel Corbett
Affiliation:
Laboratory of Biological Psychiatry, Illinois State Psychiatric Institute, Chicago, Illinois 60612
Samuel T. Christian
Affiliation:
Neurosciences Program and Department of Psychiatry, University of Alabama, University Station Birmingham, Alabama 35294
Richard D. Morin
Affiliation:
Neurosciences Program and Department of Psychiatry, University of Alabama, University Station Birmingham, Alabama 35294
Frederick Benington
Affiliation:
Neurosciences Program and Department of Psychiatry, University of Alabama, University Station Birmingham, Alabama 35294
John R. Smythies
Affiliation:
Neurosciences Program and Department of Psychiatry, University of Alabama, University Station Birmingham, Alabama 35294

Abstract

The incidence and quantities of dimethyltryptamine and O-methyl-bufotenine were studied in the cerebrospinal fluid of patients suffering acute schizophrenic illnesses and in surgical and neurological control groups. Some schizophrenic patients have higher levels of both amines than do controls, though the differences in distribution did not reach statistical significance in the sample studied. The gas-chromatographic technique used is sensitive at the low picogram level.

Type
Papers
Copyright
Copyright © Royal College of Psychiatrists, 1978 

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