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Histocompatability Antigens and Schizophrenia

Published online by Cambridge University Press:  29 January 2018

Peter McGuffin
Affiliation:
St James's Hospital, Leeds LS9 7TF
Anne E. Farmer
Affiliation:
Scalebor Park Hospital, Burley-in-Wharfedale, Yorks LS29 7AJ
S. M. Rajah
Affiliation:
Blood Transfusion Centre, Seacroft, Leeds LS15 7TW

Abstract

The HLA (Human Leucocyte Antigen) types A and B were studied in 80 patients diagnosed as schizophrenic. There was an increased incidence of HLA-BW5 and a decrease in HLA-AW29 and HLA-BW17 as compared with healthy controls. In the sub-group of patients exhibiting Schneider's first-rank symptoms there was an increased incidence of HLA-A1 with a decrease in HLA-A2 and HLA-BW17.

Type
Papers
Copyright
Copyright © Royal College of Psychiatrists, 1978 

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