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Disease Associations in Linked Records: Schizophrenia and Accidental Injury

Published online by Cambridge University Press:  29 January 2018

J. A. Baldwin
Affiliation:
Oxford University Unit of Clinical Epidemiology, Oxford Regional Health Authority, Old Road, Headington, Oxford OX3 7LF
J. K. Wing
Affiliation:
M.R.C. Social Psychiatry Unit, Institute of Psychiatry, DeCrespigny Park, London SE5

Extract

The investigation to be reported in this paper was undertaken following a query concerning the relationship between road accidents and the use of psychotropic drugs. One aspect of this problem could be studied easily by using the file of linked records of the Oxford Record Linkage Study (Acheson, 1967; Baldwin, 1973). Statistical methods have been developed to estimate the degree of association between conditions occurring in time-ordered sequences (Baldwin et al, 1978). The existing file of linked hospital discharge and death records in the Oxford Record Linkage Study was therefore searched and relevant material analysed to test the hypothesis that admission to hospital for schizophrenia was followed by an increased risk of accident or injury. (The present data do not allow the more specific question of phenothiazine treatment to be investigated). The statistical procedures simultaneously provide data on the converse situation, namely where injury occurs prior to hospital admission with schizophrenia, and this was studied also.

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1978 

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References

Acheson, E. D. (1967) Medical Record Linkage. OUP, 1967.Google Scholar
Baldwin, J. A. (1973) Linked record medical information systems. Proceedings of the Royal Society of London B., 184, 403.Google ScholarPubMed
Baldwin, J. A., Fedrick, Jean, Gill, L. E. & Simmons, H. (1978) Linked diseases in individuals. In preparation.Google Scholar
Brown, G. W. & Birley, J. L. T. (1968) Crises and life changes and the onset of schizophrenia. Journal of Health and Human Behaviour, 9, 203.Google ScholarPubMed
World Health Organization (1957) The International Classification of Diseases, Injuries and Causes of Death, Seventh Revision. Geneva.Google Scholar
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